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Immunoglobulin subclass determines ability of immunoglobulin (Ig)G to capture and activate neutrophils presented as normal human IgG or disease-associated anti-neutrophil cytoplasm antibody (ANCA)-IgG.
Pankhurst T, Nash G, Williams J, Colman R, Hussain A, Savage C. Pankhurst T, et al. Among authors: williams j. Clin Exp Immunol. 2011 May;164(2):218-26. doi: 10.1111/j.1365-2249.2011.04367.x. Epub 2011 Mar 10. Clin Exp Immunol. 2011. PMID: 21391987 Free PMC article.
Can neutrophils be manipulated in vivo?
Morgan MD, Harper L, Lu X, Nash G, Williams J, Savage CO. Morgan MD, et al. Among authors: williams j. Rheumatology (Oxford). 2005 May;44(5):597-601. doi: 10.1093/rheumatology/keh507. Epub 2004 Dec 14. Rheumatology (Oxford). 2005. PMID: 15598708 Review. No abstract available.
ANCA-associated vasculitis is linked to carriage of the Z allele of α₁ antitrypsin and its polymers.
Morris H, Morgan MD, Wood AM, Smith SW, Ekeowa UI, Herrmann K, Holle JU, Guillevin L, Lomas DA, Perez J, Pusey CD, Salama AD, Stockley R, Wieczorek S, McKnight AJ, Maxwell AP, Miranda E, Williams J, Savage CO, Harper L. Morris H, et al. Among authors: williams j. Ann Rheum Dis. 2011 Oct;70(10):1851-6. doi: 10.1136/ard.2011.153569. Epub 2011 Aug 5. Ann Rheum Dis. 2011. PMID: 21821620
Translational research in autoimmunity: aims of therapy in vasculitis.
Watts R, Harper L, Jayne D, Levy J, Pusey C, Savage C, Scott DG, Williams J. Watts R, et al. Among authors: williams j. Rheumatology (Oxford). 2005 May;44(5):573-6. doi: 10.1093/rheumatology/keh609. Epub 2005 Mar 29. Rheumatology (Oxford). 2005. PMID: 15797978 No abstract available.
Effect of Aspirin on Disability-free Survival in the Healthy Elderly.
McNeil JJ, Woods RL, Nelson MR, Reid CM, Kirpach B, Wolfe R, Storey E, Shah RC, Lockery JE, Tonkin AM, Newman AB, Williamson JD, Margolis KL, Ernst ME, Abhayaratna WP, Stocks N, Fitzgerald SM, Orchard SG, Trevaks RE, Beilin LJ, Donnan GA, Gibbs P, Johnston CI, Ryan J, Radziszewska B, Grimm R, Murray AM; ASPREE Investigator Group. McNeil JJ, et al. N Engl J Med. 2018 Oct 18;379(16):1499-1508. doi: 10.1056/NEJMoa1800722. Epub 2018 Sep 16. N Engl J Med. 2018. PMID: 30221596 Free PMC article. Clinical Trial.
Prediction of disability-free survival in healthy older people.
Neumann JT, Thao LTP, Murray AM, Callander E, Carr PR, Nelson MR, Wolfe R, Woods RL, Reid CM, Shah RC, Newman AB, Williamson JD, Tonkin AM, McNeil JJ; ASPREE investigators. Neumann JT, et al. Geroscience. 2022 Jun;44(3):1641-1655. doi: 10.1007/s11357-022-00547-x. Epub 2022 Apr 14. Geroscience. 2022. PMID: 35420334 Free PMC article. Clinical Trial.
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