Lu XH - Search Results

1

Molecular and cellular basis of obsessive-compulsive disorder-like behaviors: emerging view from mouse models.

Yang XW, Lu XH. Yang XW, et al. Among authors: lu xh. Curr Opin Neurol. 2011 Apr;24(2):114-8. doi: 10.1097/WCO.0b013e32834451fb. Curr Opin Neurol. 2011. PMID: 21386675 Review.

2

P2X4 Receptor Reporter Mice: Sparse Brain Expression and Feeding-Related Presynaptic Facilitation in the Arcuate Nucleus.

Xu J, Bernstein AM, Wong A, Lu XH, Khoja S, Yang XW, Davies DL, Micevych P, Sofroniew MV, Khakh BS. Xu J, et al. Among authors: lu xh. J Neurosci. 2016 Aug 24;36(34):8902-20. doi: 10.1523/JNEUROSCI.1496-16.2016. J Neurosci. 2016. PMID: 27559172 Free PMC article.

3

Dosage sensitivity intolerance of VIPR2 microduplication is disease causative to manifest schizophrenia-like phenotypes in a novel BAC transgenic mouse model.

Tian X, Richard A, El-Saadi MW, Bhandari A, Latimer B, Van Savage I, Holmes K, Klein RL, Dwyer D, Goeders NE, Yang XW, Lu XH. Tian X, et al. Among authors: lu xh. Mol Psychiatry. 2019 Dec;24(12):1884-1901. doi: 10.1038/s41380-019-0492-3. Epub 2019 Aug 23. Mol Psychiatry. 2019. PMID: 31444475

4

Genetically-directed Sparse Neuronal Labeling in BAC Transgenic Mice through Mononucleotide Repeat Frameshift.

Lu XH, Yang XW. Lu XH, et al. Sci Rep. 2017 Mar 8;7:43915. doi: 10.1038/srep43915. Sci Rep. 2017. PMID: 28272512 Free PMC article.

5

Full-length human mutant huntingtin with a stable polyglutamine repeat can elicit progressive and selective neuropathogenesis in BACHD mice.

Gray M, Shirasaki DI, Cepeda C, André VM, Wilburn B, Lu XH, Tao J, Yamazaki I, Li SH, Sun YE, Li XJ, Levine MS, Yang XW. Gray M, et al. Among authors: lu xh. J Neurosci. 2008 Jun 11;28(24):6182-95. doi: 10.1523/JNEUROSCI.0857-08.2008. J Neurosci. 2008. PMID: 18550760 Free PMC article.

6

Bacterial artificial chromosome transgenic mice expressing a truncated mutant parkin exhibit age-dependent hypokinetic motor deficits, dopaminergic neuron degeneration, and accumulation of proteinase K-resistant alpha-synuclein.

Lu XH, Fleming SM, Meurers B, Ackerson LC, Mortazavi F, Lo V, Hernandez D, Sulzer D, Jackson GR, Maidment NT, Chesselet MF, Yang XW. Lu XH, et al. J Neurosci. 2009 Feb 18;29(7):1962-76. doi: 10.1523/JNEUROSCI.5351-08.2009. J Neurosci. 2009. PMID: 19228951 Free PMC article.

7

Deletion of astroglial Dicer causes non-cell-autonomous neuronal dysfunction and degeneration.

Tao J, Wu H, Lin Q, Wei W, Lu XH, Cantle JP, Ao Y, Olsen RW, Yang XW, Mody I, Sofroniew MV, Sun YE. Tao J, et al. Among authors: lu xh. J Neurosci. 2011 Jun 1;31(22):8306-19. doi: 10.1523/JNEUROSCI.0567-11.2011. J Neurosci. 2011. PMID: 21632951 Free PMC article.

8

"Huntingtin holiday": progress toward an antisense therapy for Huntington's disease.

Lu XH, Yang XW. Lu XH, et al. Neuron. 2012 Jun 21;74(6):964-6. doi: 10.1016/j.neuron.2012.06.001. Neuron. 2012. PMID: 22726826 Free PMC article.

9

Neuronal targets for reducing mutant huntingtin expression to ameliorate disease in a mouse model of Huntington's disease.

Wang N, Gray M, Lu XH, Cantle JP, Holley SM, Greiner E, Gu X, Shirasaki D, Cepeda C, Li Y, Dong H, Levine MS, Yang XW. Wang N, et al. Among authors: lu xh. Nat Med. 2014 May;20(5):536-41. doi: 10.1038/nm.3514. Epub 2014 Apr 28. Nat Med. 2014. PMID: 24784230 Free PMC article.

10

An independent study of the preclinical efficacy of C2-8 in the R6/2 transgenic mouse model of Huntington's disease.

Wang N, Lu XH, Sandoval SV, Yang XW. Wang N, et al. Among authors: lu xh. J Huntingtons Dis. 2013;2(4):443-51. doi: 10.3233/JHD-130074. J Huntingtons Dis. 2013. PMID: 25062731 Free PMC article.

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