Functional activity of anti-LINGO-1 antibody opicinumab requires target engagement at a secondary binding site.
Hanf KJM, Arndt JW, Liu Y, Gong BJ, Rushe M, Sopko R, Massol R, Smith B, Gao Y, Dalkilic-Liddle I, Lee X, Mojta S, Shao Z, Mi S, Pepinsky RB.
Hanf KJM, et al. Among authors: gong bj.
MAbs. 2020 Jan-Dec;12(1):1713648. doi: 10.1080/19420862.2020.1713648.
MAbs. 2020.
PMID: 31928294
Free PMC article.