Kharasch ED - Search Results

1

Simultaneous determination of alfentanil and midazolam in human plasma using liquid chromatography and tandem mass spectrometry.

Kim T, London A, Kharasch ED. Kim T, et al. Among authors: kharasch ed. J Pharm Biomed Anal. 2011 Jun 1;55(3):487-93. doi: 10.1016/j.jpba.2011.01.040. Epub 2011 Mar 5. J Pharm Biomed Anal. 2011. PMID: 21382685 Free PMC article.

2

Gas chromatographic-mass spectrometric analysis of alfentanil metabolites. Application to human liver microsomal alfentanil biotransformation.

Labroo R, Kharasch ED. Labroo R, et al. Among authors: kharasch ed. J Chromatogr B Biomed Appl. 1994 Oct 3;660(1):85-94. doi: 10.1016/0378-4347(94)00263-0. J Chromatogr B Biomed Appl. 1994. PMID: 7858727

3

Determination of alfentanil and noralfentanil in human plasma by gas chromatography-mass spectrometry.

Mautz DS, Labroo R, Kharasch ED. Mautz DS, et al. Among authors: kharasch ed. J Chromatogr B Biomed Appl. 1994 Aug 5;658(1):149-53. doi: 10.1016/0378-4347(94)00201-0. J Chromatogr B Biomed Appl. 1994. PMID: 7952116

4

Determination of the halothane metabolites trifluoroacetic acid and bromide in plasma and urine by ion chromatography.

Hankins DC, Kharasch ED. Hankins DC, et al. Among authors: kharasch ed. J Chromatogr B Biomed Sci Appl. 1997 May 9;692(2):413-8. doi: 10.1016/s0378-4347(96)00527-0. J Chromatogr B Biomed Sci Appl. 1997. PMID: 9188831

5

Intraindividual variability in male hepatic CYP3A4 activity assessed by alfentanil and midazolam clearance.

Kharasch ED, Jubert C, Senn T, Bowdle TA, Thummel KE. Kharasch ED, et al. J Clin Pharmacol. 1999 Jul;39(7):664-9. doi: 10.1177/00912709922008290. J Clin Pharmacol. 1999. PMID: 10392320 Clinical Trial.

6

Determination of morphine and morphine glucuronides in human plasma by 96-well plate solid-phase extraction and liquid chromatography-electrospray ionization mass spectrometry.

Whittington D, Kharasch ED. Whittington D, et al. Among authors: kharasch ed. J Chromatogr B Analyt Technol Biomed Life Sci. 2003 Oct 25;796(1):95-103. doi: 10.1016/j.jchromb.2003.08.007. J Chromatogr B Analyt Technol Biomed Life Sci. 2003. PMID: 14552820

7

Stereoselective determination of methadone and the primary metabolite EDDP in human plasma by automated on-line extraction and liquid chromatography mass spectrometry.

Whittington D, Sheffels P, Kharasch ED. Whittington D, et al. Among authors: kharasch ed. J Chromatogr B Analyt Technol Biomed Life Sci. 2004 Oct 5;809(2):313-21. doi: 10.1016/j.jchromb.2004.06.041. J Chromatogr B Analyt Technol Biomed Life Sci. 2004. PMID: 15315782

8

Intravenous and oral alfentanil as in vivo probes for hepatic and first-pass cytochrome P450 3A activity: noninvasive assessment by use of pupillary miosis.

Kharasch ED, Walker A, Hoffer C, Sheffels P. Kharasch ED, et al. Clin Pharmacol Ther. 2004 Nov;76(5):452-66. doi: 10.1016/j.clpt.2004.07.006. Clin Pharmacol Ther. 2004. PMID: 15536460 Clinical Trial.

9

Single-point sampling for assessment of constitutive, induced, and inhibited cytochrome P450 3A activity with alfentanil or midazolam.

Chaobal HN, Kharasch ED. Chaobal HN, et al. Among authors: kharasch ed. Clin Pharmacol Ther. 2005 Nov;78(5):529-39. doi: 10.1016/j.clpt.2005.08.004. Clin Pharmacol Ther. 2005. PMID: 16321619 Clinical Trial.

10

Influence of CYP3A5 genotype on the pharmacokinetics and pharmacodynamics of the cytochrome P4503A probes alfentanil and midazolam.

Kharasch ED, Walker A, Isoherranen N, Hoffer C, Sheffels P, Thummel K, Whittington D, Ensign D. Kharasch ED, et al. Clin Pharmacol Ther. 2007 Oct;82(4):410-26. doi: 10.1038/sj.clpt.6100237. Epub 2007 Jun 6. Clin Pharmacol Ther. 2007. PMID: 17554244 Clinical Trial.

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