Shaul Y - Search Results

1

BIM(EL), an intrinsically disordered protein, is degraded by 20S proteasomes in the absence of poly-ubiquitylation.

Wiggins CM, Tsvetkov P, Johnson M, Joyce CL, Lamb CA, Bryant NJ, Komander D, Shaul Y, Cook SJ. Wiggins CM, et al. Among authors: shaul y. J Cell Sci. 2011 Mar 15;124(Pt 6):969-77. doi: 10.1242/jcs.058438. J Cell Sci. 2011. PMID: 21378313

2

P53 hot-spot mutants are resistant to ubiquitin-independent degradation by increased binding to NAD(P)H:quinone oxidoreductase 1.

Asher G, Lotem J, Tsvetkov P, Reiss V, Sachs L, Shaul Y. Asher G, et al. Among authors: shaul y. Proc Natl Acad Sci U S A. 2003 Dec 9;100(25):15065-70. doi: 10.1073/pnas.2436329100. Epub 2003 Nov 21. Proc Natl Acad Sci U S A. 2003. PMID: 14634213 Free PMC article.

3

A mechanism of ubiquitin-independent proteasomal degradation of the tumor suppressors p53 and p73.

Asher G, Tsvetkov P, Kahana C, Shaul Y. Asher G, et al. Among authors: shaul y. Genes Dev. 2005 Feb 1;19(3):316-21. doi: 10.1101/gad.319905. Genes Dev. 2005. PMID: 15687255 Free PMC article.

4

20S proteasomal degradation of ornithine decarboxylase is regulated by NQO1.

Asher G, Bercovich Z, Tsvetkov P, Shaul Y, Kahana C. Asher G, et al. Among authors: shaul y. Mol Cell. 2005 Mar 4;17(5):645-55. doi: 10.1016/j.molcel.2005.01.020. Mol Cell. 2005. PMID: 15749015 Free article.

5

Inhibition of NAD(P)H:quinone oxidoreductase 1 activity and induction of p53 degradation by the natural phenolic compound curcumin.

Tsvetkov P, Asher G, Reiss V, Shaul Y, Sachs L, Lotem J. Tsvetkov P, et al. Among authors: shaul y. Proc Natl Acad Sci U S A. 2005 Apr 12;102(15):5535-40. doi: 10.1073/pnas.0501828102. Epub 2005 Apr 4. Proc Natl Acad Sci U S A. 2005. PMID: 15809436 Free PMC article.

6

The crystal structure of NAD(P)H quinone oxidoreductase 1 in complex with its potent inhibitor dicoumarol.

Asher G, Dym O, Tsvetkov P, Adler J, Shaul Y. Asher G, et al. Among authors: shaul y. Biochemistry. 2006 May 23;45(20):6372-8. doi: 10.1021/bi0600087. Biochemistry. 2006. PMID: 16700548

7

Operational definition of intrinsically unstructured protein sequences based on susceptibility to the 20S proteasome.

Tsvetkov P, Asher G, Paz A, Reuven N, Sussman JL, Silman I, Shaul Y. Tsvetkov P, et al. Among authors: shaul y. Proteins. 2008 Mar;70(4):1357-66. doi: 10.1002/prot.21614. Proteins. 2008. PMID: 17879262

8

Ubiquitin-independent p53 proteasomal degradation.

Tsvetkov P, Reuven N, Shaul Y. Tsvetkov P, et al. Among authors: shaul y. Cell Death Differ. 2010 Jan;17(1):103-8. doi: 10.1038/cdd.2009.67. Cell Death Differ. 2010. PMID: 19557012 Review.

9

Susceptibility of p53 unstructured N terminus to 20 S proteasomal degradation programs the stress response.

Tsvetkov P, Reuven N, Prives C, Shaul Y. Tsvetkov P, et al. Among authors: shaul y. J Biol Chem. 2009 Sep 25;284(39):26234-42. doi: 10.1074/jbc.M109.040493. Epub 2009 Jul 17. J Biol Chem. 2009. PMID: 19617345 Free PMC article.

10

The nanny model for IDPs.

Tsvetkov P, Reuven N, Shaul Y. Tsvetkov P, et al. Among authors: shaul y. Nat Chem Biol. 2009 Nov;5(11):778-81. doi: 10.1038/nchembio.233. Nat Chem Biol. 2009. PMID: 19841623 No abstract available.

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