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Derivatization for stabilizing sialic acids in MALDI-MS.
Sekiya S, Wada Y, Tanaka K. Sekiya S, et al. Among authors: tanaka k. Anal Chem. 2005 Aug 1;77(15):4962-8. doi: 10.1021/ac050287o. Anal Chem. 2005. PMID: 16053310
In this study, we tried to stabilize the moiety by amidation, as in the case of peptides (Sekiya, S.; Wada, Y. Tanaka, K. Anal. Chem. 2004, 76, 5894-5902), and found 4-(4,6-dimethoxy-1,3,5-triazin-2yl)-4-methylmorpholinium chloride to be a desirable condensing agent …
In this study, we tried to stabilize the moiety by amidation, as in the case of peptides (Sekiya, S.; Wada, Y. Tanaka, K. Anal …
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