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Functional characterization of liver enhancers that regulate drug-associated transporters.
Kim MJ, Skewes-Cox P, Fukushima H, Hesselson S, Yee SW, Ramsey LB, Nguyen L, Eshragh JL, Castro RA, Wen CC, Stryke D, Johns SJ, Ferrin TE, Kwok PY, Relling MV, Giacomini KM, Kroetz DL, Ahituv N. Kim MJ, et al. Among authors: ahituv n. Clin Pharmacol Ther. 2011 Apr;89(4):571-8. doi: 10.1038/clpt.2010.353. Epub 2011 Mar 2. Clin Pharmacol Ther. 2011. PMID: 21368754 Free PMC article.
Identification and characterization of proximal promoter polymorphisms in the human concentrative nucleoside transporter 2 (SLC28A2).
Yee SW, Shima JE, Hesselson S, Nguyen L, De Val S, Lafond RJ, Kawamoto M, Johns SJ, Stryke D, Kwok PY, Ferrin TE, Black BL, Gurwitz D, Ahituv N, Giacomini KM. Yee SW, et al. Among authors: ahituv n. J Pharmacol Exp Ther. 2009 Mar;328(3):699-707. doi: 10.1124/jpet.108.147207. Epub 2008 Dec 19. J Pharmacol Exp Ther. 2009. PMID: 19098160 Free PMC article.
Identification and characterization of novel polymorphisms in the basal promoter of the human transporter, MATE1.
Ha Choi J, Wah Yee S, Kim MJ, Nguyen L, Ho Lee J, Kang JO, Hesselson S, Castro RA, Stryke D, Johns SJ, Kwok PY, Ferrin TE, Goo Lee M, Black BL, Ahituv N, Giacomini KM. Ha Choi J, et al. Among authors: ahituv n. Pharmacogenet Genomics. 2009 Oct;19(10):770-80. doi: 10.1097/FPC.0b013e328330eeca. Pharmacogenet Genomics. 2009. PMID: 19745787 Free PMC article.
Massively parallel functional dissection of mammalian enhancers in vivo.
Patwardhan RP, Hiatt JB, Witten DM, Kim MJ, Smith RP, May D, Lee C, Andrie JM, Lee SI, Cooper GM, Ahituv N, Pennacchio LA, Shendure J. Patwardhan RP, et al. Among authors: ahituv n. Nat Biotechnol. 2012 Feb 26;30(3):265-70. doi: 10.1038/nbt.2136. Nat Biotechnol. 2012. PMID: 22371081 Free PMC article.
Coding exons function as tissue-specific enhancers of nearby genes.
Birnbaum RY, Clowney EJ, Agamy O, Kim MJ, Zhao J, Yamanaka T, Pappalardo Z, Clarke SL, Wenger AM, Nguyen L, Gurrieri F, Everman DB, Schwartz CE, Birk OS, Bejerano G, Lomvardas S, Ahituv N. Birnbaum RY, et al. Among authors: ahituv n. Genome Res. 2012 Jun;22(6):1059-68. doi: 10.1101/gr.133546.111. Epub 2012 Mar 22. Genome Res. 2012. PMID: 22442009 Free PMC article.
174 results