Thorburn A - Search Results

1

Distinct TRAIL resistance mechanisms can be overcome by proteasome inhibition but not generally by synergizing agents.

Menke C, Bin L, Thorburn J, Behbakht K, Ford HL, Thorburn A. Menke C, et al. Among authors: thorburn a, thorburn j. Cancer Res. 2011 Mar 1;71(5):1883-92. doi: 10.1158/0008-5472.CAN-10-2252. Cancer Res. 2011. PMID: 21363923 Free PMC article.

2

Tumor-derived mutations in the TRAIL receptor DR5 inhibit TRAIL signaling through the DR4 receptor by competing for ligand binding.

Bin L, Thorburn J, Thomas LR, Clark PE, Humphreys R, Thorburn A. Bin L, et al. Among authors: thorburn a, thorburn j. J Biol Chem. 2007 Sep 21;282(38):28189-94. doi: 10.1074/jbc.M704210200. Epub 2007 Jul 31. J Biol Chem. 2007. PMID: 17666396 Free article.

3

TRAIL receptor-targeted therapeutics: resistance mechanisms and strategies to avoid them.

Thorburn A, Behbakht K, Ford H. Thorburn A, et al. Drug Resist Updat. 2008 Feb-Apr;11(1-2):17-24. doi: 10.1016/j.drup.2008.02.001. Epub 2008 Apr 18. Drug Resist Updat. 2008. PMID: 18374623 Free PMC article. Review.

4

EGFR-targeted diphtheria toxin stimulates TRAIL killing of glioblastoma cells by depleting anti-apoptotic proteins.

Horita H, Thorburn J, Frankel AE, Thorburn A. Horita H, et al. Among authors: thorburn a, thorburn j. J Neurooncol. 2009 Nov;95(2):175-184. doi: 10.1007/s11060-009-9914-4. Epub 2009 May 17. J Neurooncol. 2009. PMID: 19449148 Free PMC article.

5

TRAIL receptor signaling regulation of chemosensitivity in vivo but not in vitro.

Menke C, Goncharov T, Qamar L, Korch C, Ford HL, Behbakht K, Thorburn A. Menke C, et al. Among authors: thorburn a. PLoS One. 2011 Jan 14;6(1):e14527. doi: 10.1371/journal.pone.0014527. PLoS One. 2011. PMID: 21264287 Free PMC article.

6

Non-cell-autonomous Effects of Autophagy Inhibition in Tumor Cells Promote Growth of Drug-resistant Cells.

Thorburn J, Staskiewicz L, Goodall ML, Dimberg L, Frankel AE, Ford HL, Thorburn A. Thorburn J, et al. Among authors: thorburn a. Mol Pharmacol. 2017 Jan;91(1):58-64. doi: 10.1124/mol.116.106070. Epub 2016 Nov 9. Mol Pharmacol. 2017. PMID: 27974637 Free PMC article.

7

A Genome-Wide Loss-of-Function Screen Identifies SLC26A2 as a Novel Mediator of TRAIL Resistance.

Dimberg LY, Towers CG, Behbakht K, Hotz TJ, Kim J, Fosmire S, Porter CC, Tan AC, Thorburn A, Ford HL. Dimberg LY, et al. Among authors: thorburn a. Mol Cancer Res. 2017 Apr;15(4):382-394. doi: 10.1158/1541-7786.MCR-16-0234. Epub 2017 Jan 20. Mol Cancer Res. 2017. PMID: 28108622 Free PMC article.

8

Six1 overexpression in ovarian carcinoma causes resistance to TRAIL-mediated apoptosis and is associated with poor survival.

Behbakht K, Qamar L, Aldridge CS, Coletta RD, Davidson SA, Thorburn A, Ford HL. Behbakht K, et al. Among authors: thorburn a. Cancer Res. 2007 Apr 1;67(7):3036-42. doi: 10.1158/0008-5472.CAN-06-3755. Cancer Res. 2007. PMID: 17409410

9

On the TRAIL to successful cancer therapy? Predicting and counteracting resistance against TRAIL-based therapeutics.

Dimberg LY, Anderson CK, Camidge R, Behbakht K, Thorburn A, Ford HL. Dimberg LY, et al. Among authors: thorburn a. Oncogene. 2013 Mar 14;32(11):1341-50. doi: 10.1038/onc.2012.164. Epub 2012 May 14. Oncogene. 2013. PMID: 22580613 Free PMC article. Review.

10

Regulation of HMGB1 release by autophagy.

Thorburn J, Frankel AE, Thorburn A. Thorburn J, et al. Among authors: thorburn a. Autophagy. 2009 Feb;5(2):247-9. doi: 10.4161/auto.5.2.7552. Epub 2009 Feb 5. Autophagy. 2009. PMID: 19098461 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

254 results

Search Page

Filters