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The A/G allele of rs16906252 predicts for MGMT methylation and is selectively silenced in premalignant lesions from smokers and in lung adenocarcinomas.
Leng S, Bernauer AM, Hong C, Do KC, Yingling CM, Flores KG, Tessema M, Tellez CS, Willink RP, Burki EA, Picchi MA, Stidley CA, Prados MD, Costello JF, Gilliland FD, Crowell RE, Belinsky SA. Leng S, et al. Among authors: costello jf. Clin Cancer Res. 2011 Apr 1;17(7):2014-23. doi: 10.1158/1078-0432.CCR-10-3026. Epub 2011 Feb 25. Clin Cancer Res. 2011. PMID: 21355081 Free PMC article.
Phase II and pharmacogenomics study of enzastaurin plus temozolomide during and following radiation therapy in patients with newly diagnosed glioblastoma multiforme and gliosarcoma.
Butowski N, Chang SM, Lamborn KR, Polley MY, Pieper R, Costello JF, Vandenberg S, Parvataneni R, Nicole A, Sneed PK, Clarke J, Hsieh E, Costa BM, Reis RM, Hristova-Kazmierski M, Nicol SJ, Thornton DE, Prados MD. Butowski N, et al. Among authors: costello jf. Neuro Oncol. 2011 Dec;13(12):1331-8. doi: 10.1093/neuonc/nor130. Epub 2011 Sep 6. Neuro Oncol. 2011. PMID: 21896554 Free PMC article. Clinical Trial.
Abnormal DNA methylation of CD133 in colorectal and glioblastoma tumors.
Yi JM, Tsai HC, Glöckner SC, Lin S, Ohm JE, Easwaran H, James CD, Costello JF, Riggins G, Eberhart CG, Laterra J, Vescovi AL, Ahuja N, Herman JG, Schuebel KE, Baylin SB. Yi JM, et al. Among authors: costello jf. Cancer Res. 2008 Oct 1;68(19):8094-103. doi: 10.1158/0008-5472.CAN-07-6208. Cancer Res. 2008. PMID: 18829568 Free PMC article.
256 results