B1 receptors as a new inflammatory target. Could this B the 1?
Ahluwalia A, Perretti M.
Ahluwalia A, et al.
Trends Pharmacol Sci. 1999 Mar;20(3):100-4. doi: 10.1016/s0165-6147(99)01321-8.
Trends Pharmacol Sci. 1999.
PMID: 10203864
The endogenous ligand for the B1 receptor is des-arg9BK, a cleavage product of the activity of carboxypeptidase on BK. Activation of B1 receptors produces a range of pro-inflammatory effects including oedema, pain and promotion of blood-borne leukocyte trafficking. …
The endogenous ligand for the B1 receptor is des-arg9BK, a cleavage product of the activity of carboxypeptidase on BK. Activation of …