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Small molecule inhibitors of Staphylococcus aureus RnpA alter cellular mRNA turnover, exhibit antimicrobial activity, and attenuate pathogenesis.
Olson PD, Kuechenmeister LJ, Anderson KL, Daily S, Beenken KE, Roux CM, Reniere ML, Lewis TL, Weiss WJ, Pulse M, Nguyen P, Simecka JW, Morrison JM, Sayood K, Asojo OA, Smeltzer MS, Skaar EP, Dunman PM. Olson PD, et al. Among authors: skaar ep. PLoS Pathog. 2011 Feb 10;7(2):e1001287. doi: 10.1371/journal.ppat.1001287. PLoS Pathog. 2011. PMID: 21347352 Free PMC article.
Metal chelation and inhibition of bacterial growth in tissue abscesses.
Corbin BD, Seeley EH, Raab A, Feldmann J, Miller MR, Torres VJ, Anderson KL, Dattilo BM, Dunman PM, Gerads R, Caprioli RM, Nacken W, Chazin WJ, Skaar EP. Corbin BD, et al. Among authors: skaar ep. Science. 2008 Feb 15;319(5865):962-5. doi: 10.1126/science.1152449. Science. 2008. PMID: 18276893
Staphylococcus aureus fur regulates the expression of virulence factors that contribute to the pathogenesis of pneumonia.
Torres VJ, Attia AS, Mason WJ, Hood MI, Corbin BD, Beasley FC, Anderson KL, Stauff DL, McDonald WH, Zimmerman LJ, Friedman DB, Heinrichs DE, Dunman PM, Skaar EP. Torres VJ, et al. Among authors: skaar ep. Infect Immun. 2010 Apr;78(4):1618-28. doi: 10.1128/IAI.01423-09. Epub 2010 Jan 25. Infect Immun. 2010. PMID: 20100857 Free PMC article.
271 results