Rucktooa P - Search Results

1

Fragment growing induces conformational changes in acetylcholine-binding protein: a structural and thermodynamic analysis.

Edink E, Rucktooa P, Retra K, Akdemir A, Nahar T, Zuiderveld O, van Elk R, Janssen E, van Nierop P, van Muijlwijk-Koezen J, Smit AB, Sixma TK, Leurs R, de Esch IJ. Edink E, et al. Among authors: rucktooa p. J Am Chem Soc. 2011 Apr 13;133(14):5363-71. doi: 10.1021/ja110571r. Epub 2011 Feb 15. J Am Chem Soc. 2011. PMID: 21322593

2

Insight in nAChR subtype selectivity from AChBP crystal structures.

Rucktooa P, Smit AB, Sixma TK. Rucktooa P, et al. Biochem Pharmacol. 2009 Oct 1;78(7):777-87. doi: 10.1016/j.bcp.2009.06.098. Epub 2009 Jul 1. Biochem Pharmacol. 2009. PMID: 19576182 Review.

3

Acetylcholine binding protein (AChBP) as template for hierarchical in silico screening procedures to identify structurally novel ligands for the nicotinic receptors.

Akdemir A, Rucktooa P, Jongejan A, Elk Rv, Bertrand S, Sixma TK, Bertrand D, Smit AB, Leurs R, de Graaf C, de Esch IJ. Akdemir A, et al. Among authors: rucktooa p. Bioorg Med Chem. 2011 Oct 15;19(20):6107-19. doi: 10.1016/j.bmc.2011.08.028. Epub 2011 Aug 27. Bioorg Med Chem. 2011. PMID: 21920761

4

Assembly of a π-π stack of ligands in the binding site of an acetylcholine-binding protein.

Stornaiuolo M, De Kloe GE, Rucktooa P, Fish A, van Elk R, Edink ES, Bertrand D, Smit AB, de Esch IJ, Sixma TK. Stornaiuolo M, et al. Among authors: rucktooa p. Nat Commun. 2013;4:1875. doi: 10.1038/ncomms2900. Nat Commun. 2013. PMID: 23695669 Free PMC article.

5

Structural characterization of binding mode of smoking cessation drugs to nicotinic acetylcholine receptors through study of ligand complexes with acetylcholine-binding protein.

Rucktooa P, Haseler CA, van Elk R, Smit AB, Gallagher T, Sixma TK. Rucktooa P, et al. J Biol Chem. 2012 Jul 6;287(28):23283-93. doi: 10.1074/jbc.M112.360347. Epub 2012 May 2. J Biol Chem. 2012. PMID: 22553201 Free PMC article.

6

Interaction of alpha-conotoxin ImII and its analogs with nicotinic receptors and acetylcholine-binding proteins: additional binding sites on Torpedo receptor.

Kasheverov IE, Zhmak MN, Fish A, Rucktooa P, Khruschov AY, Osipov AV, Ziganshin RH, D'hoedt D, Bertrand D, Sixma TK, Smit AB, Tsetlin VI. Kasheverov IE, et al. Among authors: rucktooa p. J Neurochem. 2009 Nov;111(4):934-44. doi: 10.1111/j.1471-4159.2009.06359.x. Epub 2009 Aug 27. J Neurochem. 2009. PMID: 19712060 Free article.

7

Structure of UBE2Z Enzyme Provides Functional Insight into Specificity in the FAT10 Protein Conjugation Machinery.

Schelpe J, Monté D, Dewitte F, Sixma TK, Rucktooa P. Schelpe J, et al. Among authors: rucktooa p. J Biol Chem. 2016 Jan 8;291(2):630-9. doi: 10.1074/jbc.M115.671545. Epub 2015 Nov 10. J Biol Chem. 2016. PMID: 26555268 Free PMC article.

8

Dimeric α-cobratoxin X-ray structure: localization of intermolecular disulfides and possible mode of binding to nicotinic acetylcholine receptors.

Osipov AV, Rucktooa P, Kasheverov IE, Filkin SY, Starkov VG, Andreeva TV, Sixma TK, Bertrand D, Utkin YN, Tsetlin VI. Osipov AV, et al. Among authors: rucktooa p. J Biol Chem. 2012 Feb 24;287(9):6725-34. doi: 10.1074/jbc.M111.322313. Epub 2012 Jan 5. J Biol Chem. 2012. PMID: 22223648 Free PMC article.

9

Exploring drug target flexibility using in situ click chemistry: application to a mycobacterial transcriptional regulator.

Willand N, Desroses M, Toto P, Dirié B, Lens Z, Villeret V, Rucktooa P, Locht C, Baulard A, Deprez B. Willand N, et al. Among authors: rucktooa p. ACS Chem Biol. 2010 Nov 19;5(11):1007-13. doi: 10.1021/cb100177g. ACS Chem Biol. 2010. PMID: 20704273

10

Characterization of ERM transactivation domain binding to the ACID/PTOV domain of the Mediator subunit MED25.

Landrieu I, Verger A, Baert JL, Rucktooa P, Cantrelle FX, Dewitte F, Ferreira E, Lens Z, Villeret V, Monté D. Landrieu I, et al. Among authors: rucktooa p. Nucleic Acids Res. 2015 Aug 18;43(14):7110-21. doi: 10.1093/nar/gkv650. Epub 2015 Jun 29. Nucleic Acids Res. 2015. PMID: 26130716 Free PMC article.

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