Eaton JB - Search Results

1

Synthesis of 2-(substituted phenyl)-3,5,5-trimethylmorpholine analogues and their effects on monoamine uptake, nicotinic acetylcholine receptor function, and behavioral effects of nicotine.

Carroll FI, Muresan AZ, Blough BE, Navarro HA, Mascarella SW, Eaton JB, Huang X, Damaj MI, Lukas RJ. Carroll FI, et al. Among authors: eaton jb. J Med Chem. 2011 Mar 10;54(5):1441-8. doi: 10.1021/jm1014555. Epub 2011 Feb 14. J Med Chem. 2011. PMID: 21319801 Free PMC article.

2

Tobacco cembranoids block behavioral sensitization to nicotine and inhibit neuronal acetylcholine receptor function.

Ferchmin PA, Lukas RJ, Hann RM, Fryer JD, Eaton JB, Pagán OR, Rodríguez AD, Nicolau Y, Rosado M, Cortés S, Eterović VA. Ferchmin PA, et al. Among authors: eaton jb. J Neurosci Res. 2001 Apr 1;64(1):18-25. doi: 10.1002/jnr.1049. J Neurosci Res. 2001. PMID: 11276047

3

Characterization of human alpha 4 beta 2-nicotinic acetylcholine receptors stably and heterologously expressed in native nicotinic receptor-null SH-EP1 human epithelial cells.

Eaton JB, Peng JH, Schroeder KM, George AA, Fryer JD, Krishnan C, Buhlman L, Kuo YP, Steinlein O, Lukas RJ. Eaton JB, et al. Mol Pharmacol. 2003 Dec;64(6):1283-94. doi: 10.1124/mol.64.6.1283. Mol Pharmacol. 2003. PMID: 14645658

4

Enantioselective effects of hydroxy metabolites of bupropion on behavior and on function of monoamine transporters and nicotinic receptors.

Damaj MI, Carroll FI, Eaton JB, Navarro HA, Blough BE, Mirza S, Lukas RJ, Martin BR. Damaj MI, et al. Among authors: eaton jb. Mol Pharmacol. 2004 Sep;66(3):675-82. doi: 10.1124/mol.104.001313. Mol Pharmacol. 2004. PMID: 15322260

5

Roles for nicotinic acetylcholine receptor subunit large cytoplasmic loop sequences in receptor expression and function.

Kuo YP, Xu L, Eaton JB, Zhao L, Wu J, Lukas RJ. Kuo YP, et al. Among authors: eaton jb. J Pharmacol Exp Ther. 2005 Jul;314(1):455-66. doi: 10.1124/jpet.105.084954. Epub 2005 Apr 15. J Pharmacol Exp Ther. 2005. PMID: 15833891

6

Chemistry and pharmacology of nicotinic ligands based on 6-[5-(azetidin-2-ylmethoxy)pyridin-3-yl]hex-5-yn-1-ol (AMOP-H-OH) for possible use in depression.

Kozikowski AP, Eaton JB, Bajjuri KM, Chellappan SK, Chen Y, Karadi S, He R, Caldarone B, Manzano M, Yuen PW, Lukas RJ. Kozikowski AP, et al. Among authors: eaton jb. ChemMedChem. 2009 Aug;4(8):1279-91. doi: 10.1002/cmdc.200900079. ChemMedChem. 2009. PMID: 19569163 Free PMC article.

7

Synthesis and biological evaluation of bupropion analogues as potential pharmacotherapies for smoking cessation.

Carroll FI, Blough BE, Mascarella SW, Navarro HA, Eaton JB, Lukas RJ, Damaj MI. Carroll FI, et al. Among authors: eaton jb. J Med Chem. 2010 Mar 11;53(5):2204-14. doi: 10.1021/jm9017465. J Med Chem. 2010. PMID: 20158204 Free PMC article.

8

Synthesis and characterization of in vitro and in vivo profiles of hydroxybupropion analogues: aids to smoking cessation.

Lukas RJ, Muresan AZ, Damaj MI, Blough BE, Huang X, Navarro HA, Mascarella SW, Eaton JB, Marxer-Miller SK, Carroll FI. Lukas RJ, et al. Among authors: eaton jb. J Med Chem. 2010 Jun 24;53(12):4731-48. doi: 10.1021/jm1003232. J Med Chem. 2010. PMID: 20509659 Free PMC article.

9

Chemistry and pharmacological characterization of novel nitrogen analogues of AMOP-H-OH (Sazetidine-A, 6-[5-(azetidin-2-ylmethoxy)pyridin-3-yl]hex-5-yn-1-ol) as α4β2-nicotinic acetylcholine receptor-selective partial agonists.

Liu J, Eaton JB, Caldarone B, Lukas RJ, Kozikowski AP. Liu J, et al. Among authors: eaton jb. J Med Chem. 2010 Oct 14;53(19):6973-85. doi: 10.1021/jm100765u. J Med Chem. 2010. PMID: 20822184 Free PMC article.

10

Nicotinic acetylcholine receptor efficacy and pharmacological properties of 3-(substituted phenyl)-2β-substituted tropanes.

Carroll FI, Blough BE, Mascarella SW, Navarro HA, Eaton JB, Lukas RJ, Damaj MI. Carroll FI, et al. Among authors: eaton jb. J Med Chem. 2010 Dec 9;53(23):8345-53. doi: 10.1021/jm100994w. Epub 2010 Nov 8. J Med Chem. 2010. PMID: 21058665 Free PMC article.

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