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A comparative integrated transcript analysis and functional characterization of differential mechanisms for induction of liver hypertrophy in the rat.
Boitier E, Amberg A, Barbié V, Blichenberg A, Brandenburg A, Gmuender H, Gruhler A, McCarthy D, Meyer K, Riefke B, Raschke M, Schoonen W, Sieber M, Suter L, Thomas CE, Sajot N. Boitier E, et al. Among authors: gmuender h. Toxicol Appl Pharmacol. 2011 Apr 15;252(2):85-96. doi: 10.1016/j.taap.2011.01.021. Epub 2011 Feb 26. Toxicol Appl Pharmacol. 2011. PMID: 21315101
The enhanced value of combining conventional and "omics" analyses in early assessment of drug-induced hepatobiliary injury.
Ellinger-Ziegelbauer H, Adler M, Amberg A, Brandenburg A, Callanan JJ, Connor S, Fountoulakis M, Gmuender H, Gruhler A, Hewitt P, Hodson M, Matheis KA, McCarthy D, Raschke M, Riefke B, Schmitt CS, Sieber M, Sposny A, Suter L, Sweatman B, Mally A. Ellinger-Ziegelbauer H, et al. Among authors: gmuender h. Toxicol Appl Pharmacol. 2011 Apr 15;252(2):97-111. doi: 10.1016/j.taap.2010.09.022. Epub 2010 Oct 1. Toxicol Appl Pharmacol. 2011. PMID: 20888850
EU framework 6 project: predictive toxicology (PredTox)--overview and outcome.
Suter L, Schroeder S, Meyer K, Gautier JC, Amberg A, Wendt M, Gmuender H, Mally A, Boitier E, Ellinger-Ziegelbauer H, Matheis K, Pfannkuch F. Suter L, et al. Among authors: gmuender h. Toxicol Appl Pharmacol. 2011 Apr 15;252(2):73-84. doi: 10.1016/j.taap.2010.10.008. Epub 2010 Oct 16. Toxicol Appl Pharmacol. 2011. PMID: 20955723
Cross-study and cross-omics comparisons of three nephrotoxic compounds reveal mechanistic insights and new candidate biomarkers.
Matheis KA, Com E, Gautier JC, Guerreiro N, Brandenburg A, Gmuender H, Sposny A, Hewitt P, Amberg A, Boernsen O, Riefke B, Hoffmann D, Mally A, Kalkuhl A, Suter L, Dieterle F, Staedtler F. Matheis KA, et al. Among authors: gmuender h. Toxicol Appl Pharmacol. 2011 Apr 15;252(2):112-22. doi: 10.1016/j.taap.2010.11.006. Epub 2010 Nov 21. Toxicol Appl Pharmacol. 2011. PMID: 21081137
Inter-laboratory study of human in vitro toxicogenomics-based tests as alternative methods for evaluating chemical carcinogenicity: a bioinformatics perspective.
Herwig R, Gmuender H, Corvi R, Bloch KM, Brandenburg A, Castell J, Ceelen L, Chesne C, Doktorova TY, Jennen D, Jennings P, Limonciel A, Lock EA, McMorrow T, Phrakonkham P, Radford R, Slattery C, Stierum R, Vilardell M, Wittenberger T, Yildirimman R, Ryan M, Rogiers V, Kleinjans J. Herwig R, et al. Among authors: gmuender h. Arch Toxicol. 2016 Sep;90(9):2215-2229. doi: 10.1007/s00204-015-1617-3. Epub 2015 Nov 2. Arch Toxicol. 2016. PMID: 26525393
Human embryonic stem cell derived hepatocyte-like cells as a tool for in vitro hazard assessment of chemical carcinogenicity.
Yildirimman R, Brolén G, Vilardell M, Eriksson G, Synnergren J, Gmuender H, Kamburov A, Ingelman-Sundberg M, Castell J, Lahoz A, Kleinjans J, van Delft J, Björquist P, Herwig R. Yildirimman R, et al. Among authors: gmuender h. Toxicol Sci. 2011 Dec;124(2):278-90. doi: 10.1093/toxsci/kfr225. Epub 2011 Aug 27. Toxicol Sci. 2011. PMID: 21873647 Free PMC article.
Transcriptomic responses generated by hepatocarcinogens in a battery of liver-based in vitro models.
Doktorova TY, Yildirimman R, Vinken M, Vilardell M, Vanhaecke T, Gmuender H, Bort R, Brolen G, Holmgren G, Li R, Chesne C, van Delft J, Kleinjans J, Castell J, Bjorquist P, Herwig R, Rogiers V. Doktorova TY, et al. Among authors: gmuender h. Carcinogenesis. 2013 Jun;34(6):1393-402. doi: 10.1093/carcin/bgt054. Epub 2013 Feb 7. Carcinogenesis. 2013. PMID: 23393228
The carcinoGENOMICS project: critical selection of model compounds for the development of omics-based in vitro carcinogenicity screening assays.
Vinken M, Doktorova T, Ellinger-Ziegelbauer H, Ahr HJ, Lock E, Carmichael P, Roggen E, van Delft J, Kleinjans J, Castell J, Bort R, Donato T, Ryan M, Corvi R, Keun H, Ebbels T, Athersuch T, Sansone SA, Rocca-Serra P, Stierum R, Jennings P, Pfaller W, Gmuender H, Vanhaecke T, Rogiers V. Vinken M, et al. Among authors: gmuender h. Mutat Res. 2008 Sep-Oct;659(3):202-10. doi: 10.1016/j.mrrev.2008.04.006. Epub 2008 Apr 26. Mutat Res. 2008. PMID: 18514569 Review.
Testing chemical carcinogenicity by using a transcriptomics HepaRG-based model?
Doktorova TY, Yildirimman R, Ceelen L, Vilardell M, Vanhaecke T, Vinken M, Ates G, Heymans A, Gmuender H, Bort R, Corvi R, Phrakonkham P, Li R, Mouchet N, Chesne C, van Delft J, Kleinjans J, Castell J, Herwig R, Rogiers V. Doktorova TY, et al. Among authors: gmuender h. EXCLI J. 2014 May 28;13:623-37. eCollection 2014. EXCLI J. 2014. PMID: 26417288 Free PMC article.
42 results