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The transcription factor IFN regulatory factor-4 controls experimental colitis in mice via T cell-derived IL-6.
Mudter J, Amoussina L, Schenk M, Yu J, Brüstle A, Weigmann B, Atreya R, Wirtz S, Becker C, Hoffman A, Atreya I, Biesterfeld S, Galle PR, Lehr HA, Rose-John S, Mueller C, Lohoff M, Neurath MF. Mudter J, et al. Among authors: brustle a. J Clin Invest. 2008 Jul;118(7):2415-26. doi: 10.1172/JCI33227. J Clin Invest. 2008. PMID: 18535667 Free PMC article.
IL-17A secretion by CD8+ T cells supports Th17-mediated autoimmune encephalomyelitis.
Huber M, Heink S, Pagenstecher A, Reinhard K, Ritter J, Visekruna A, Guralnik A, Bollig N, Jeltsch K, Heinemann C, Wittmann E, Buch T, Prazeres da Costa O, Brüstle A, Brenner D, Mak TW, Mittrücker HW, Tackenberg B, Kamradt T, Lohoff M. Huber M, et al. Among authors: brustle a. J Clin Invest. 2013 Jan;123(1):247-60. doi: 10.1172/JCI63681. Epub 2012 Dec 10. J Clin Invest. 2013. PMID: 23221338 Free PMC article.
A hyperactive mutant of interferon-regulatory factor 4.
Kang CH, Hartmann E, Menke L, Staudenraus D, Abass EF, Raifer H, Porapu A, Camara B, Brüstle A, Pinkenburg O, Bieringer M, Lohoff M. Kang CH, et al. Among authors: brustle a. Eur J Immunol. 2019 May;49(5):812-815. doi: 10.1002/eji.201847530. Epub 2018 Sep 30. Eur J Immunol. 2019. PMID: 30218581 Free article.
IL-27 inhibits the development of regulatory T cells via STAT3.
Huber M, Steinwald V, Guralnik A, Brüstle A, Kleemann P, Rosenplänter C, Decker T, Lohoff M. Huber M, et al. Among authors: brustle a. Int Immunol. 2008 Feb;20(2):223-34. doi: 10.1093/intimm/dxm139. Epub 2007 Dec 21. Int Immunol. 2008. PMID: 18156621
Transcription factor IRF4 determines germinal center formation through follicular T-helper cell differentiation.
Bollig N, Brüstle A, Kellner K, Ackermann W, Abass E, Raifer H, Camara B, Brendel C, Giel G, Bothur E, Huber M, Paul C, Elli A, Kroczek RA, Nurieva R, Dong C, Jacob R, Mak TW, Lohoff M. Bollig N, et al. Among authors: brustle a. Proc Natl Acad Sci U S A. 2012 May 29;109(22):8664-9. doi: 10.1073/pnas.1205834109. Epub 2012 May 2. Proc Natl Acad Sci U S A. 2012. PMID: 22552227 Free PMC article.
48 results