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A novel N-ethyl-N-nitrosourea-induced mutation in phospholipase Cγ2 causes inflammatory arthritis, metabolic defects, and male infertility in vitro in a murine model.
Abe K, Fuchs H, Boersma A, Hans W, Yu P, Kalaydjiev S, Klaften M, Adler T, Calzada-Wack J, Mossbrugger I, Rathkolb B, Rozman J, Prehn C, Maraslioglu M, Kametani Y, Shimada S, Adamski J, Busch DH, Esposito I, Klingenspor M, Wolf E, Wurst W, Gailus-Durner V, Katan M, Marschall S, Soewarto D, Wagner S, de Angelis MH. Abe K, et al. Arthritis Rheum. 2011 May;63(5):1301-11. doi: 10.1002/art.30280. Arthritis Rheum. 2011. PMID: 21305534 Free article.
The First Scube3 Mutant Mouse Line with Pleiotropic Phenotypic Alterations.
Fuchs H, Sabrautzki S, Przemeck GK, Leuchtenberger S, Lorenz-Depiereux B, Becker L, Rathkolb B, Horsch M, Garrett L, Östereicher MA, Hans W, Abe K, Sagawa N, Rozman J, Vargas-Panesso IL, Sandholzer M, Lisse TS, Adler T, Aguilar-Pimentel JA, Calzada-Wack J, Ehrhard N, Elvert R, Gau C, Hölter SM, Micklich K, Moreth K, Prehn C, Puk O, Racz I, Stoeger C, Vernaleken A, Michel D, Diener S, Wieland T, Adamski J, Bekeredjian R, Busch DH, Favor J, Graw J, Klingenspor M, Lengger C, Maier H, Neff F, Ollert M, Stoeger T, Yildirim AÖ, Strom TM, Zimmer A, Wolf E, Wurst W, Klopstock T, Beckers J, Gailus-Durner V, Hrabé de Angelis M. Fuchs H, et al. Among authors: abe k. G3 (Bethesda). 2016 Dec 7;6(12):4035-4046. doi: 10.1534/g3.116.033670. G3 (Bethesda). 2016. PMID: 27815347 Free PMC article.
Characterization of phospholipase C gamma enzymes with gain-of-function mutations.
Everett KL, Bunney TD, Yoon Y, Rodrigues-Lima F, Harris R, Driscoll PC, Abe K, Fuchs H, de Angelis MH, Yu P, Cho W, Katan M. Everett KL, et al. Among authors: abe k. J Biol Chem. 2009 Aug 21;284(34):23083-93. doi: 10.1074/jbc.M109.019265. Epub 2009 Jun 16. J Biol Chem. 2009. PMID: 19531496 Free PMC article.
A genetic screen for modifiers of the delta1-dependent notch signaling function in the mouse.
Rubio-Aliaga I, Soewarto D, Wagner S, Klaften M, Fuchs H, Kalaydjiev S, Busch DH, Klempt M, Rathkolb B, Wolf E, Abe K, Zeiser S, Przemeck GK, Beckers J, de Angelis MH. Rubio-Aliaga I, et al. Among authors: abe k. Genetics. 2007 Mar;175(3):1451-63. doi: 10.1534/genetics.106.067298. Epub 2006 Dec 18. Genetics. 2007. PMID: 17179084 Free PMC article.
ER stress-mediated apoptosis in a new mouse model of osteogenesis imperfecta.
Lisse TS, Thiele F, Fuchs H, Hans W, Przemeck GK, Abe K, Rathkolb B, Quintanilla-Martinez L, Hoelzlwimmer G, Helfrich M, Wolf E, Ralston SH, Hrabé de Angelis M. Lisse TS, et al. Among authors: abe k. PLoS Genet. 2008 Feb;4(2):e7. doi: 10.1371/journal.pgen.0040007. PLoS Genet. 2008. PMID: 18248096 Free PMC article.
7,001 results