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Unbiased screening of polymer libraries to define novel substrates for functional hepatocytes with inducible drug metabolism.
Hay DC, Pernagallo S, Diaz-Mochon JJ, Medine CN, Greenhough S, Hannoun Z, Schrader J, Black JR, Fletcher J, Dalgetty D, Thompson AI, Newsome PN, Forbes SJ, Ross JA, Bradley M, Iredale JP. Hay DC, et al. Among authors: fletcher j. Stem Cell Res. 2011 Mar;6(2):92-102. doi: 10.1016/j.scr.2010.12.002. Epub 2010 Dec 10. Stem Cell Res. 2011. PMID: 21277274 Free article.
Highly efficient differentiation of hESCs to functional hepatic endoderm requires ActivinA and Wnt3a signaling.
Hay DC, Fletcher J, Payne C, Terrace JD, Gallagher RC, Snoeys J, Black JR, Wojtacha D, Samuel K, Hannoun Z, Pryde A, Filippi C, Currie IS, Forbes SJ, Ross JA, Newsome PN, Iredale JP. Hay DC, et al. Among authors: fletcher j. Proc Natl Acad Sci U S A. 2008 Aug 26;105(34):12301-6. doi: 10.1073/pnas.0806522105. Epub 2008 Aug 21. Proc Natl Acad Sci U S A. 2008. PMID: 18719101 Free PMC article.
Generation of functional human hepatic endoderm from human induced pluripotent stem cells.
Sullivan GJ, Hay DC, Park IH, Fletcher J, Hannoun Z, Payne CM, Dalgetty D, Black JR, Ross JA, Samuel K, Wang G, Daley GQ, Lee JH, Church GM, Forbes SJ, Iredale JP, Wilmut I. Sullivan GJ, et al. Among authors: fletcher j. Hepatology. 2010 Jan;51(1):329-35. doi: 10.1002/hep.23335. Hepatology. 2010. PMID: 19877180 Free PMC article.
Mutant induced pluripotent stem cell lines recapitulate aspects of TDP-43 proteinopathies and reveal cell-specific vulnerability.
Bilican B, Serio A, Barmada SJ, Nishimura AL, Sullivan GJ, Carrasco M, Phatnani HP, Puddifoot CA, Story D, Fletcher J, Park IH, Friedman BA, Daley GQ, Wyllie DJ, Hardingham GE, Wilmut I, Finkbeiner S, Maniatis T, Shaw CE, Chandran S. Bilican B, et al. Among authors: fletcher j. Proc Natl Acad Sci U S A. 2012 Apr 10;109(15):5803-8. doi: 10.1073/pnas.1202922109. Epub 2012 Mar 26. Proc Natl Acad Sci U S A. 2012. PMID: 22451909 Free PMC article.
4,283 results