Mosbacher J - Search Results

1

Exploring subtype selectivity and metabolic stability of a novel series of ligands for the benzodiazepine binding site of the GABAA receptor.

Hintermann S, Hurth K, Nozulak J, Tintelnot-Blomley M, Aichholz R, Blanz J, Kaupmann K, Mosbacher J. Hintermann S, et al. Among authors: mosbacher j. Bioorg Med Chem Lett. 2011 Mar 1;21(5):1523-6. doi: 10.1016/j.bmcl.2010.12.107. Epub 2010 Dec 28. Bioorg Med Chem Lett. 2011. PMID: 21277199

2

N,N'-Dicyclopentyl-2-methylsulfanyl-5-nitro-pyrimidine-4,6-diamine (GS39783) and structurally related compounds: novel allosteric enhancers of gamma-aminobutyric acidB receptor function.

Urwyler S, Pozza MF, Lingenhoehl K, Mosbacher J, Lampert C, Froestl W, Koller M, Kaupmann K. Urwyler S, et al. Among authors: mosbacher j. J Pharmacol Exp Ther. 2003 Oct;307(1):322-30. doi: 10.1124/jpet.103.053074. Epub 2003 Sep 3. J Pharmacol Exp Ther. 2003. PMID: 12954816

3

Selected amino acids, dipeptides and arylalkylamine derivatives do not act as allosteric modulators at GABAB receptors.

Urwyler S, Gjoni T, Kaupmann K, Pozza MF, Mosbacher J. Urwyler S, et al. Among authors: mosbacher j. Eur J Pharmacol. 2004 Jan 12;483(2-3):147-53. doi: 10.1016/j.ejphar.2003.10.024. Eur J Pharmacol. 2004. PMID: 14729102

4

Molecular structure and physiological functions of GABA(B) receptors.

Bettler B, Kaupmann K, Mosbacher J, Gassmann M. Bettler B, et al. Among authors: mosbacher j. Physiol Rev. 2004 Jul;84(3):835-67. doi: 10.1152/physrev.00036.2003. Physiol Rev. 2004. PMID: 15269338 Free article. Review.

5

Point mutations in the transmembrane region of GABAB2 facilitate activation by the positive modulator N,N'-dicyclopentyl-2-methylsulfanyl-5-nitro-pyrimidine-4,6-diamine (GS39783) in the absence of the GABAB1 subunit.

Dupuis DS, Relkovic D, Lhuillier L, Mosbacher J, Kaupmann K. Dupuis DS, et al. Among authors: mosbacher j. Mol Pharmacol. 2006 Dec;70(6):2027-36. doi: 10.1124/mol.106.028183. Epub 2006 Sep 11. Mol Pharmacol. 2006. PMID: 16966477

6

Specific gamma-hydroxybutyrate-binding sites but loss of pharmacological effects of gamma-hydroxybutyrate in GABA(B)(1)-deficient mice.

Kaupmann K, Cryan JF, Wellendorph P, Mombereau C, Sansig G, Klebs K, Schmutz M, Froestl W, van der Putten H, Mosbacher J, Bräuner-Osborne H, Waldmeier P, Bettler B. Kaupmann K, et al. Among authors: mosbacher j. Eur J Neurosci. 2003 Nov;18(10):2722-30. doi: 10.1111/j.1460-9568.2003.03013.x. Eur J Neurosci. 2003. PMID: 14656321

7

Determination of the minimal functional ligand-binding domain of the GABAB1b receptor.

Deriu D, Gassmann M, Firbank S, Ristig D, Lampert C, Mosbacher J, Froestl W, Kaupmann K, Bettler B, Grütter MG. Deriu D, et al. Among authors: mosbacher j. Biochem J. 2005 Mar 15;386(Pt 3):423-31. doi: 10.1042/BJ20040804. Biochem J. 2005. PMID: 15482257 Free PMC article.

8

Coupling of human nicotinic acetylcholine receptors alpha 7 to calcium channels in GH3 cells.

Feuerbach D, Lingenhöhl K, Dobbins P, Mosbacher J, Corbett N, Nozulak J, Hoyer D. Feuerbach D, et al. Among authors: mosbacher j. Neuropharmacology. 2005 Feb;48(2):215-27. doi: 10.1016/j.neuropharm.2004.10.003. Epub 2004 Dec 24. Neuropharmacology. 2005. PMID: 15695160

9

The N-terminal domain of gamma-aminobutyric Acid(B) receptors is sufficient to specify agonist and antagonist binding.

Malitschek B, Schweizer C, Keir M, Heid J, Froestl W, Mosbacher J, Kuhn R, Henley J, Joly C, Pin JP, Kaupmann K, Bettler B. Malitschek B, et al. Among authors: mosbacher j. Mol Pharmacol. 1999 Aug;56(2):448-54. doi: 10.1124/mol.56.2.448. Mol Pharmacol. 1999. PMID: 10419566

10

Gamma-hydroxybutyrate is a weak agonist at recombinant GABA(B) receptors.

Lingenhoehl K, Brom R, Heid J, Beck P, Froestl W, Kaupmann K, Bettler B, Mosbacher J. Lingenhoehl K, et al. Among authors: mosbacher j. Neuropharmacology. 1999 Nov;38(11):1667-73. doi: 10.1016/s0028-3908(99)00131-8. Neuropharmacology. 1999. PMID: 10587082

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