Shinkura R - Search Results

1

Mice carrying a knock-in mutation of Aicda resulting in a defect in somatic hypermutation have impaired gut homeostasis and compromised mucosal defense.

Wei M, Shinkura R, Doi Y, Maruya M, Fagarasan S, Honjo T. Wei M, et al. Among authors: shinkura r. Nat Immunol. 2011 Mar;12(3):264-70. doi: 10.1038/ni.1991. Epub 2011 Jan 23. Nat Immunol. 2011. PMID: 21258321

2

Oral administration of lipopolysaccharides activates B-1 cells in the peritoneal cavity and lamina propria of the gut and induces autoimmune symptoms in an autoantibody transgenic mouse.

Murakami M, Tsubata T, Shinkura R, Nisitani S, Okamoto M, Yoshioka H, Usui T, Miyawaki S, Honjo T. Murakami M, et al. Among authors: shinkura r. J Exp Med. 1994 Jul 1;180(1):111-21. doi: 10.1084/jem.180.1.111. J Exp Med. 1994. PMID: 8006578 Free PMC article.

3

Defects of somatic hypermutation and class switching in alymphoplasia (aly) mutant mice.

Shinkura R, Matsuda F, Sakiyama T, Tsubata T, Hiai H, Paumen M, Miyawaki S, Honjo T. Shinkura R, et al. Int Immunol. 1996 Jul;8(7):1067-75. doi: 10.1093/intimm/8.7.1067. Int Immunol. 1996. PMID: 8757952

4

Autoimmune disease of exocrine organs in immunodeficient alymphoplasia mice: a spontaneous model for Sjögren's syndrome.

Tsubata R, Tsubata T, Hiai H, Shinkura R, Matsumura R, Sumida T, Miyawaki S, Ishida H, Kumagai S, Nakao K, Honjo T. Tsubata R, et al. Among authors: shinkura r. Eur J Immunol. 1996 Nov;26(11):2742-8. doi: 10.1002/eji.1830261129. Eur J Immunol. 1996. PMID: 8921964

5

Alymphoplasia is caused by a point mutation in the mouse gene encoding Nf-kappa b-inducing kinase.

Shinkura R, Kitada K, Matsuda F, Tashiro K, Ikuta K, Suzuki M, Kogishi K, Serikawa T, Honjo T. Shinkura R, et al. Nat Genet. 1999 May;22(1):74-7. doi: 10.1038/8780. Nat Genet. 1999. PMID: 10319865

6

Alymphoplasia (aly)-type nuclear factor kappaB-inducing kinase (NIK) causes defects in secondary lymphoid tissue chemokine receptor signaling and homing of peritoneal cells to the gut-associated lymphatic tissue system.

Fagarasan S, Shinkura R, Kamata T, Nogaki F, Ikuta K, Tashiro K, Honjo T. Fagarasan S, et al. Among authors: shinkura r. J Exp Med. 2000 May 1;191(9):1477-86. doi: 10.1084/jem.191.9.1477. J Exp Med. 2000. PMID: 10790423 Free PMC article.

7

Mechanism of B1 cell differentiation and migration in GALT.

Fagarasan S, Shinkura R, Kamata T, Nogaki F, Ikuta K, Honjo T. Fagarasan S, et al. Among authors: shinkura r. Curr Top Microbiol Immunol. 2000;252:221-9. doi: 10.1007/978-3-642-57284-5_23. Curr Top Microbiol Immunol. 2000. PMID: 11125479 No abstract available.

8

Activation-induced cytidine deaminase shuttles between nucleus and cytoplasm like apolipoprotein B mRNA editing catalytic polypeptide 1.

Ito S, Nagaoka H, Shinkura R, Begum N, Muramatsu M, Nakata M, Honjo T. Ito S, et al. Among authors: shinkura r. Proc Natl Acad Sci U S A. 2004 Feb 17;101(7):1975-80. doi: 10.1073/pnas.0307335101. Epub 2004 Feb 9. Proc Natl Acad Sci U S A. 2004. PMID: 14769937 Free PMC article.

9

Separate domains of AID are required for somatic hypermutation and class-switch recombination.

Shinkura R, Ito S, Begum NA, Nagaoka H, Muramatsu M, Kinoshita K, Sakakibara Y, Hijikata H, Honjo T. Shinkura R, et al. Nat Immunol. 2004 Jul;5(7):707-12. doi: 10.1038/ni1086. Epub 2004 Jun 13. Nat Immunol. 2004. PMID: 15195091

10

De novo protein synthesis is required for activation-induced cytidine deaminase-dependent DNA cleavage in immunoglobulin class switch recombination.

Begum NA, Kinoshita K, Muramatsu M, Nagaoka H, Shinkura R, Honjo T. Begum NA, et al. Among authors: shinkura r. Proc Natl Acad Sci U S A. 2004 Aug 31;101(35):13003-7. doi: 10.1073/pnas.0405219101. Epub 2004 Aug 18. Proc Natl Acad Sci U S A. 2004. PMID: 15317942 Free PMC article.

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