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Spirodiketopiperazine-based CCR5 antagonist: discovery of an antiretroviral drug candidate.
Nishizawa R, Nishiyama T, Hisaichi K, Minamoto C, Matsunaga N, Takaoka Y, Nakai H, Jenkinson S, Kazmierski WM, Tada H, Sagawa K, Shibayama S, Fukushima D, Maeda K, Mitsuya H. Nishizawa R, et al. Among authors: matsunaga n. Bioorg Med Chem Lett. 2011 Feb 15;21(4):1141-5. doi: 10.1016/j.bmcl.2010.12.109. Epub 2010 Dec 28. Bioorg Med Chem Lett. 2011. PMID: 21256008 Free PMC article.
Discovery of a novel EP2/EP4 dual agonist with high subtype-selectivity.
Kambe T, Maruyama T, Nakano M, Nakai Y, Yoshida T, Matsunaga N, Oida H, Konaka A, Maruyama T, Nakai H, Toda M. Kambe T, et al. Among authors: matsunaga n. Bioorg Med Chem Lett. 2012 Jan 1;22(1):396-401. doi: 10.1016/j.bmcl.2011.10.109. Epub 2011 Nov 7. Bioorg Med Chem Lett. 2012. PMID: 22119471
Discovery of a Slow Tight Binding LPA1 Antagonist (ONO-0300302) for the Treatment of Benign Prostatic Hyperplasia.
Terakado M, Suzuki H, Hashimura K, Tanaka M, Ueda H, Hirai K, Asada M, Ikura M, Matsunaga N, Saga H, Shinozaki K, Karakawa N, Takada Y, Minami M, Egashira H, Sugiura Y, Yamada M, Nakade S, Takaoka Y. Terakado M, et al. Among authors: matsunaga n. ACS Med Chem Lett. 2017 Nov 20;8(12):1281-1286. doi: 10.1021/acsmedchemlett.7b00383. eCollection 2017 Dec 14. ACS Med Chem Lett. 2017. PMID: 29259748 Free PMC article.
ONO-LB-457: a novel and orally active leukotriene B4 receptor antagonist.
Kishikawa K, Matsunaga N, Maruyama T, Seo R, Toda M, Miyamoto T, Kawasaki A. Kishikawa K, et al. Among authors: matsunaga n. Adv Prostaglandin Thromboxane Leukot Res. 1991;21A:407-10. Adv Prostaglandin Thromboxane Leukot Res. 1991. PMID: 1847777 No abstract available.
865 results