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Page 1
LHON gene therapy vector prevents visual loss and optic neuropathy induced by G11778A mutant mitochondrial DNA: biodistribution and toxicology profile.
Koilkonda R, Yu H, Talla V, Porciatti V, Feuer WJ, Hauswirth WW, Chiodo V, Erger KE, Boye SL, Lewin AS, Conlon TJ, Renner L, Neuringer M, Detrisac C, Guy J. Koilkonda R, et al. Invest Ophthalmol Vis Sci. 2014 Oct 23;55(12):7739-53. doi: 10.1167/iovs.14-15388. Invest Ophthalmol Vis Sci. 2014. PMID: 25342621 Free PMC article.
Gene delivery to mitochondria by targeting modified adenoassociated virus suppresses Leber's hereditary optic neuropathy in a mouse model.
Yu H, Koilkonda RD, Chou TH, Porciatti V, Ozdemir SS, Chiodo V, Boye SL, Boye SE, Hauswirth WW, Lewin AS, Guy J. Yu H, et al. Among authors: koilkonda rd. Proc Natl Acad Sci U S A. 2012 May 15;109(20):E1238-47. doi: 10.1073/pnas.1119577109. Epub 2012 Apr 20. Proc Natl Acad Sci U S A. 2012. PMID: 22523243 Free PMC article.
Gene Therapy for Leber Hereditary Optic Neuropathy: Initial Results.
Feuer WJ, Schiffman JC, Davis JL, Porciatti V, Gonzalez P, Koilkonda RD, Yuan H, Lalwani A, Lam BL, Guy J. Feuer WJ, et al. Among authors: koilkonda rd. Ophthalmology. 2016 Mar;123(3):558-70. doi: 10.1016/j.ophtha.2015.10.025. Epub 2015 Nov 19. Ophthalmology. 2016. PMID: 26606867 Free PMC article. Clinical Trial.
17 results