Buhtoiarov IN - Search Results

1

Differential internalization of hu14.18-IL2 immunocytokine by NK and tumor cell: impact on conjugation, cytotoxicity, and targeting.

Buhtoiarov IN, Neal ZC, Gan J, Buhtoiarova TN, Patankar MS, Gubbels JA, Hank JA, Yamane B, Rakhmilevich AL, Reisfeld RA, Gillies SD, Sondel PM. Buhtoiarov IN, et al. J Leukoc Biol. 2011 Apr;89(4):625-38. doi: 10.1189/jlb.0710422. Epub 2011 Jan 19. J Leukoc Biol. 2011. PMID: 21248148 Free PMC article.

2

Enhanced activity of hu14.18-IL2 immunocytokine against murine NXS2 neuroblastoma when combined with interleukin 2 therapy.

Neal ZC, Yang JC, Rakhmilevich AL, Buhtoiarov IN, Lum HE, Imboden M, Hank JA, Lode HN, Reisfeld RA, Gillies SD, Sondel PM. Neal ZC, et al. Among authors: buhtoiarov in. Clin Cancer Res. 2004 Jul 15;10(14):4839-47. doi: 10.1158/1078-0432.CCR-03-0799. Clin Cancer Res. 2004. PMID: 15269160

3

CD40 ligation activates murine macrophages via an IFN-gamma-dependent mechanism resulting in tumor cell destruction in vitro.

Buhtoiarov IN, Lum H, Berke G, Paulnock DM, Sondel PM, Rakhmilevich AL. Buhtoiarov IN, et al. J Immunol. 2005 May 15;174(10):6013-22. doi: 10.4049/jimmunol.174.10.6013. J Immunol. 2005. PMID: 15879094

4

In vivo CD40 ligation can induce T-cell-independent antitumor effects that involve macrophages.

Lum HD, Buhtoiarov IN, Schmidt BE, Berke G, Paulnock DM, Sondel PM, Rakhmilevich AL. Lum HD, et al. Among authors: buhtoiarov in. J Leukoc Biol. 2006 Jun;79(6):1181-92. doi: 10.1189/jlb.0405191. Epub 2006 Mar 24. J Leukoc Biol. 2006. PMID: 16565324

5

Intratumoral immunocytokine treatment results in enhanced antitumor effects.

Johnson EE, Lum HD, Rakhmilevich AL, Schmidt BE, Furlong M, Buhtoiarov IN, Hank JA, Raubitschek A, Colcher D, Reisfeld RA, Gillies SD, Sondel PM. Johnson EE, et al. Among authors: buhtoiarov in. Cancer Immunol Immunother. 2008 Dec;57(12):1891-902. doi: 10.1007/s00262-008-0519-0. Epub 2008 Apr 26. Cancer Immunol Immunother. 2008. PMID: 18438664 Free PMC article.

6

Radiofrequency ablation combined with KS-IL2 immunocytokine (EMD 273066) results in an enhanced antitumor effect against murine colon adenocarcinoma.

Johnson EE, Yamane BH, Buhtoiarov IN, Lum HD, Rakhmilevich AL, Mahvi DM, Gillies SD, Sondel PM. Johnson EE, et al. Among authors: buhtoiarov in. Clin Cancer Res. 2009 Aug 1;15(15):4875-84. doi: 10.1158/1078-0432.CCR-09-0110. Epub 2009 Jul 28. Clin Cancer Res. 2009. PMID: 19638464 Free PMC article.

7

Ab-IL2 fusion proteins mediate NK cell immune synapse formation by polarizing CD25 to the target cell-effector cell interface.

Gubbels JA, Gadbaw B, Buhtoiarov IN, Horibata S, Kapur AK, Patel D, Hank JA, Gillies SD, Sondel PM, Patankar MS, Connor J. Gubbels JA, et al. Among authors: buhtoiarov in. Cancer Immunol Immunother. 2011 Dec;60(12):1789-800. doi: 10.1007/s00262-011-1072-9. Epub 2011 Jul 27. Cancer Immunol Immunother. 2011. PMID: 21792658 Free PMC article.

8

Synergistic activation of macrophages via CD40 and TLR9 results in T cell independent antitumor effects.

Buhtoiarov IN, Lum HD, Berke G, Sondel PM, Rakhmilevich AL. Buhtoiarov IN, et al. J Immunol. 2006 Jan 1;176(1):309-18. doi: 10.4049/jimmunol.176.1.309. J Immunol. 2006. PMID: 16365423

9

Tumoristatic effects of anti-CD40 mAb-activated macrophages involve nitric oxide and tumour necrosis factor-alpha.

Lum HD, Buhtoiarov IN, Schmidt BE, Berke G, Paulnock DM, Sondel PM, Rakhmilevich AL. Lum HD, et al. Among authors: buhtoiarov in. Immunology. 2006 Jun;118(2):261-70. doi: 10.1111/j.1365-2567.2006.02366.x. Immunology. 2006. PMID: 16771862 Free PMC article.

10

Macrophages are essential for antitumour effects against weakly immunogenic murine tumours induced by class B CpG-oligodeoxynucleotides.

Buhtoiarov IN, Sondel PM, Eickhoff JC, Rakhmilevich AL. Buhtoiarov IN, et al. Immunology. 2007 Mar;120(3):412-23. doi: 10.1111/j.1365-2567.2006.02517.x. Epub 2006 Dec 8. Immunology. 2007. PMID: 17163960 Free PMC article.

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