Bruning J - Search Results

1

The TB Structural Genomics Consortium: a decade of progress.

Chim N, Habel JE, Johnston JM, Krieger I, Miallau L, Sankaranarayanan R, Morse RP, Bruning J, Swanson S, Kim H, Kim CY, Li H, Bulloch EM, Payne RJ, Manos-Turvey A, Hung LW, Baker EN, Lott JS, James MN, Terwilliger TC, Eisenberg DS, Sacchettini JC, Goulding CW. Chim N, et al. Among authors: bruning j. Tuberculosis (Edinb). 2011 Mar;91(2):155-72. doi: 10.1016/j.tube.2010.11.009. Epub 2011 Jan 17. Tuberculosis (Edinb). 2011. PMID: 21247804 Free PMC article. Review.

2

Structural insights into the mechanism of the allosteric transitions of Mycobacterium tuberculosis cAMP receptor protein.

Reddy MCM, Palaninathan SK, Bruning JB, Thurman C, Smith D, Sacchettini JC. Reddy MCM, et al. J Biol Chem. 2009 Dec 25;284(52):36581-36591. doi: 10.1074/jbc.M109.041343. Epub 2009 Sep 9. J Biol Chem. 2009. PMID: 19740754 Free PMC article.

3

Structure of the Mycobacterium tuberculosis D-alanine:D-alanine ligase, a target of the antituberculosis drug D-cycloserine.

Bruning JB, Murillo AC, Chacon O, Barletta RG, Sacchettini JC. Bruning JB, et al. Antimicrob Agents Chemother. 2011 Jan;55(1):291-301. doi: 10.1128/AAC.00558-10. Epub 2010 Oct 18. Antimicrob Agents Chemother. 2011. PMID: 20956591 Free PMC article.

4

Structure of the apo form of Bacillus stearothermophilus phosphofructokinase.

Mosser R, Reddy MC, Bruning JB, Sacchettini JC, Reinhart GD. Mosser R, et al. Biochemistry. 2012 Jan 24;51(3):769-75. doi: 10.1021/bi201548p. Epub 2012 Jan 11. Biochemistry. 2012. PMID: 22212099 Free PMC article.

5

Redefining the role of the quaternary shift in Bacillus stearothermophilus phosphofructokinase.

Mosser R, Reddy MC, Bruning JB, Sacchettini JC, Reinhart GD. Mosser R, et al. Biochemistry. 2013 Aug 13;52(32):5421-9. doi: 10.1021/bi4002503. Epub 2013 Jul 31. Biochemistry. 2013. PMID: 23859543 Free PMC article.

6

Structure, activity, and inhibition of the Carboxyltransferase β-subunit of acetyl coenzyme A carboxylase (AccD6) from Mycobacterium tuberculosis.

Reddy MC, Breda A, Bruning JB, Sherekar M, Valluru S, Thurman C, Ehrenfeld H, Sacchettini JC. Reddy MC, et al. Antimicrob Agents Chemother. 2014 Oct;58(10):6122-32. doi: 10.1128/AAC.02574-13. Epub 2014 Aug 4. Antimicrob Agents Chemother. 2014. PMID: 25092705 Free PMC article.

7

Structural mechanism for signal transduction in RXR nuclear receptor heterodimers.

Kojetin DJ, Matta-Camacho E, Hughes TS, Srinivasan S, Nwachukwu JC, Cavett V, Nowak J, Chalmers MJ, Marciano DP, Kamenecka TM, Shulman AI, Rance M, Griffin PR, Bruning JB, Nettles KW. Kojetin DJ, et al. Among authors: bruning jb. Nat Commun. 2015 Aug 20;6:8013. doi: 10.1038/ncomms9013. Nat Commun. 2015. PMID: 26289479 Free PMC article.

8

Sulfonamide-Based Inhibitors of Biotin Protein Ligase as New Antibiotic Leads.

Lee KJ, Tieu W, Blanco-Rodriguez B, Paparella AS, Yu J, Hayes A, Feng J, Marshall AC, Noll B, Milne R, Cini D, Wilce MCJ, Booker GW, Bruning JB, Polyak SW, Abell AD. Lee KJ, et al. Among authors: bruning jb. ACS Chem Biol. 2019 Sep 20;14(9):1990-1997. doi: 10.1021/acschembio.9b00463. Epub 2019 Aug 21. ACS Chem Biol. 2019. PMID: 31407891

9

Precipitant-ligand exchange technique reveals the ADP binding mode in Mycobacterium tuberculosis dethiobiotin synthetase.

Thompson AP, Wegener KL, Booker GW, Polyak SW, Bruning JB. Thompson AP, et al. Acta Crystallogr D Struct Biol. 2018 Oct 1;74(Pt 10):965-972. doi: 10.1107/S2059798318010136. Epub 2018 Oct 2. Acta Crystallogr D Struct Biol. 2018. PMID: 30289406

10

Chemical Crosslinking Mass Spectrometry Reveals the Conformational Landscape of the Activation Helix of PPARγ; a Model for Ligand-Dependent Antagonism.

Zheng J, Corzo C, Chang MR, Shang J, Lam VQ, Brust R, Blayo AL, Bruning JB, Kamenecka TM, Kojetin DJ, Griffin PR. Zheng J, et al. Among authors: bruning jb. Structure. 2018 Nov 6;26(11):1431-1439.e6. doi: 10.1016/j.str.2018.07.007. Epub 2018 Aug 23. Structure. 2018. PMID: 30146169 Free PMC article.

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