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The Ghent Marfan Trial--a randomized, double-blind placebo controlled trial with losartan in Marfan patients treated with β-blockers.
Möberg K, De Nobele S, Devos D, Goetghebeur E, Segers P, Trachet B, Vervaet C, Renard M, Coucke P, Loeys B, De Paepe A, De Backer J. Möberg K, et al. Among authors: coucke p. Int J Cardiol. 2012 Jun 14;157(3):354-8. doi: 10.1016/j.ijcard.2010.12.070. Epub 2011 Jan 15. Int J Cardiol. 2012. PMID: 21239069 Clinical Trial.
Novel MYH11 and ACTA2 mutations reveal a role for enhanced TGFβ signaling in FTAAD.
Renard M, Callewaert B, Baetens M, Campens L, MacDermot K, Fryns JP, Bonduelle M, Dietz HC, Gaspar IM, Cavaco D, Stattin EL, Schrander-Stumpel C, Coucke P, Loeys B, De Paepe A, De Backer J. Renard M, et al. Among authors: coucke p. Int J Cardiol. 2013 May 10;165(2):314-21. doi: 10.1016/j.ijcard.2011.08.079. Epub 2011 Sep 19. Int J Cardiol. 2013. PMID: 21937134 Free PMC article.
Absence of cardiovascular manifestations in a haploinsufficient Tgfbr1 mouse model.
Renard M, Trachet B, Casteleyn C, Campens L, Cornillie P, Callewaert B, Deleye S, Vandeghinste B, van Heijningen PM, Dietz H, De Vos F, Essers J, Staelens S, Segers P, Loeys B, Coucke P, De Paepe A, De Backer J. Renard M, et al. Among authors: coucke p. PLoS One. 2014 Feb 24;9(2):e89749. doi: 10.1371/journal.pone.0089749. eCollection 2014. PLoS One. 2014. PMID: 24587008 Free PMC article.
538 results