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The severe short stature in two siblings with a heterozygous IGF1 mutation is not caused by a dominant negative effect of the putative truncated protein.
van Duyvenvoorde HA, van Doorn J, Koenig J, Gauguin L, Oostdijk W, Wade JD, Karperien M, Ruivenkamp CA, Losekoot M, van Setten PA, Walenkamp MJ, Noordam C, De Meyts P, Wit JM. van Duyvenvoorde HA, et al. Among authors: wade jd. Growth Horm IGF Res. 2011 Feb;21(1):44-50. doi: 10.1016/j.ghir.2010.12.004. Epub 2011 Jan 14. Growth Horm IGF Res. 2011. PMID: 21237682
Short stature associated with a novel heterozygous mutation in the insulin-like growth factor 1 gene.
van Duyvenvoorde HA, van Setten PA, Walenkamp MJ, van Doorn J, Koenig J, Gauguin L, Oostdijk W, Ruivenkamp CA, Losekoot M, Wade JD, De Meyts P, Karperien M, Noordam C, Wit JM. van Duyvenvoorde HA, et al. Among authors: wade jd. J Clin Endocrinol Metab. 2010 Nov;95(11):E363-7. doi: 10.1210/jc.2010-0511. Epub 2010 Jul 28. J Clin Endocrinol Metab. 2010. PMID: 20668042
Engineering of a Biologically Active Glycosylated Glucagon-Like Peptide-1 Analogue.
Chandrashekar C, Lin F, Nishiuchi Y, Mohammed SF, White BF, Arsenakis Y, Yuliantie E, Zhao P, van Dun S, Koijen A, Kajihara Y, Wootten D, Dodd GT, van den Bos LJ, Wade JD, Hossain MA. Chandrashekar C, et al. Among authors: wade jd. J Med Chem. 2024 May 9;67(9):7276-7282. doi: 10.1021/acs.jmedchem.4c00093. Epub 2024 Mar 11. J Med Chem. 2024. PMID: 38465973
COVID-19 Causes Ciliary Dysfunction as Demonstrated by Human Intranasal Micro-Optical Coherence Tomography Imaging.
Vijaykumar K, Leung HM, Barrios A, Fernandez-Petty CM, Solomon GM, Hathorne HY, Wade JD, Monroe K, Slaten KB, Li Q, Leal SM Jr, Moates DB, Pierce HM, Olson KR, Currier P, Foster S, Marsden D, Tearney GJ, Rowe SM. Vijaykumar K, et al. Among authors: wade jd. Am J Respir Cell Mol Biol. 2023 Nov;69(5):592-595. doi: 10.1165/rcmb.2023-0177LE. Am J Respir Cell Mol Biol. 2023. PMID: 38195114 Free PMC article. No abstract available.
Big peptide drugs in a small molecule world.
Otvos L Jr, Wade JD. Otvos L Jr, et al. Among authors: wade jd. Front Chem. 2023 Dec 7;11:1302169. doi: 10.3389/fchem.2023.1302169. eCollection 2023. Front Chem. 2023. PMID: 38144886 Free PMC article. Review.
Glycosylation Improves the Proteolytic Stability of Exenatide.
Chandrashekar C, Nishiuchi Y, White BF, Arsenakis Y, Lin F, McNeill SM, Zhao P, van Dun S, Koijen A, Kajihara Y, Wootten D, van den Bos LJ, Wade JD, Hossain MA. Chandrashekar C, et al. Among authors: wade jd. Bioconjug Chem. 2023 Jun 21;34(6):1014-1018. doi: 10.1021/acs.bioconjchem.3c00120. Epub 2023 May 16. Bioconjug Chem. 2023. PMID: 37192432
Editorial: Innovators in chemical biology.
Wade JD, Renaudet O, Coleman MA. Wade JD, et al. Front Chem. 2022 Nov 4;10:1074759. doi: 10.3389/fchem.2022.1074759. eCollection 2022. Front Chem. 2022. PMID: 36405327 Free PMC article. No abstract available.
Editorial: Editors' showcase: Chemical biology.
Wade JD. Wade JD. Front Chem. 2022 Aug 15;10:1004363. doi: 10.3389/fchem.2022.1004363. eCollection 2022. Front Chem. 2022. PMID: 36046732 Free PMC article. No abstract available.
286 results