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The specificity of nitroxyl chemistry is unique among nitrogen oxides in biological systems.
Flores-Santana W, Salmon DJ, Donzelli S, Switzer CH, Basudhar D, Ridnour L, Cheng R, Glynn SA, Paolocci N, Fukuto JM, Miranda KM, Wink DA. Flores-Santana W, et al. Among authors: switzer ch. Antioxid Redox Signal. 2011 May 1;14(9):1659-74. doi: 10.1089/ars.2010.3841. Epub 2011 Mar 16. Antioxid Redox Signal. 2011. PMID: 21235346 Free PMC article. Review.
The activation of metabolites of nitric oxide synthase by metals is both redox and oxygen dependent: a new feature of nitrogen oxide signaling.
Donzelli S, Switzer CH, Thomas DD, Ridnour LA, Espey MG, Isenberg JS, Tocchetti CG, King SB, Lazzarino G, Miranda KM, Roberts DD, Feelisch M, Wink DA. Donzelli S, et al. Among authors: switzer ch. Antioxid Redox Signal. 2006 Jul-Aug;8(7-8):1363-71. doi: 10.1089/ars.2006.8.1363. Antioxid Redox Signal. 2006. PMID: 16910783 Review.
The emergence of nitroxyl (HNO) as a pharmacological agent.
Switzer CH, Flores-Santana W, Mancardi D, Donzelli S, Basudhar D, Ridnour LA, Miranda KM, Fukuto JM, Paolocci N, Wink DA. Switzer CH, et al. Biochim Biophys Acta. 2009 Jul;1787(7):835-40. doi: 10.1016/j.bbabio.2009.04.015. Epub 2009 May 6. Biochim Biophys Acta. 2009. PMID: 19426703 Free PMC article. Review.
Comparing the chemical biology of NO and HNO.
Flores-Santana W, Switzer C, Ridnour LA, Basudhar D, Mancardi D, Donzelli S, Thomas DD, Miranda KM, Fukuto JM, Wink DA. Flores-Santana W, et al. Arch Pharm Res. 2009 Aug;32(8):1139-53. doi: 10.1007/s12272-009-1805-x. Epub 2009 Aug 29. Arch Pharm Res. 2009. PMID: 19727606
Nitroxyl (HNO): chemistry, biochemistry, and pharmacology.
Fukuto JM, Switzer CH, Miranda KM, Wink DA. Fukuto JM, et al. Among authors: switzer ch. Annu Rev Pharmacol Toxicol. 2005;45:335-55. doi: 10.1146/annurev.pharmtox.45.120403.095959. Annu Rev Pharmacol Toxicol. 2005. PMID: 15822180 Review.
Biological nitric oxide signalling: chemistry and terminology.
Heinrich TA, da Silva RS, Miranda KM, Switzer CH, Wink DA, Fukuto JM. Heinrich TA, et al. Among authors: switzer ch. Br J Pharmacol. 2013 Aug;169(7):1417-29. doi: 10.1111/bph.12217. Br J Pharmacol. 2013. PMID: 23617570 Free PMC article. Review.
43 results