López-Izquierdo A - Search Results

1

Structural bases for the different anti-fibrillatory effects of chloroquine and quinidine.

Noujaim SF, Stuckey JA, Ponce-Balbuena D, Ferrer-Villada T, López-Izquierdo A, Pandit SV, Sánchez-Chapula JA, Jalife J. Noujaim SF, et al. Cardiovasc Res. 2011 Mar 1;89(4):862-9. doi: 10.1093/cvr/cvr008. Epub 2011 Jan 13. Cardiovasc Res. 2011. PMID: 21233253 Free PMC article.

2

Specific residues of the cytoplasmic domains of cardiac inward rectifier potassium channels are effective antifibrillatory targets.

Noujaim SF, Stuckey JA, Ponce-Balbuena D, Ferrer-Villada T, López-Izquierdo A, Pandit S, Calvo CJ, Grzeda KR, Berenfeld O, Chapula JA, Jalife J. Noujaim SF, et al. FASEB J. 2010 Nov;24(11):4302-12. doi: 10.1096/fj.10-163246. Epub 2010 Jun 28. FASEB J. 2010. PMID: 20585026 Free PMC article.

3

Chloroquine blocks a mutant Kir2.1 channel responsible for short QT syndrome and normalizes repolarization properties in silico.

Lopez-Izquierdo A, Ponce-Balbuena D, Ferrer T, Sachse FB, Tristani-Firouzi M, Sanchez-Chapula JA. Lopez-Izquierdo A, et al. Cell Physiol Biochem. 2009;24(3-4):153-60. doi: 10.1159/000233241. Epub 2009 Aug 3. Cell Physiol Biochem. 2009. PMID: 19710529 Free PMC article.

4

The antimalarial drug mefloquine inhibits cardiac inward rectifier K+ channels: evidence for interference in PIP2-channel interaction.

López-Izquierdo A, Ponce-Balbuena D, Moreno-Galindo EG, Aréchiga-Figueroa IA, Rodríguez-Martínez M, Ferrer T, Rodríguez-Menchaca AA, Sánchez-Chapula JA. López-Izquierdo A, et al. J Cardiovasc Pharmacol. 2011 Apr;57(4):407-15. doi: 10.1097/FJC.0b013e31820b7c03. J Cardiovasc Pharmacol. 2011. PMID: 21502926

5

Molecular mechanisms of chloroquine inhibition of heterologously expressed Kir6.2/SUR2A channels.

Ponce-Balbuena D, Rodríguez-Menchaca AA, López-Izquierdo A, Ferrer T, Kurata HT, Nichols CG, Sánchez-Chapula JA. Ponce-Balbuena D, et al. Among authors: lopez izquierdo a. Mol Pharmacol. 2012 Nov;82(5):803-13. doi: 10.1124/mol.112.079152. Epub 2012 Jul 31. Mol Pharmacol. 2012. PMID: 22851715 Free PMC article.

6

Tamoxifen inhibits inward rectifier K+ 2.x family of inward rectifier channels by interfering with phosphatidylinositol 4,5-bisphosphate-channel interactions.

Ponce-Balbuena D, López-Izquierdo A, Ferrer T, Rodríguez-Menchaca AA, Aréchiga-Figueroa IA, Sánchez-Chapula JA. Ponce-Balbuena D, et al. J Pharmacol Exp Ther. 2009 Nov;331(2):563-73. doi: 10.1124/jpet.109.156075. Epub 2009 Aug 4. J Pharmacol Exp Ther. 2009. PMID: 19654266

7

Thiopental inhibits function of different inward rectifying potassium channel isoforms by a similar mechanism.

López-Izquierdo A, Ponce-Balbuena D, Ferrer T, Rodríguez-Menchaca AA, Sánchez-Chapula JA. López-Izquierdo A, et al. Eur J Pharmacol. 2010 Jul 25;638(1-3):33-41. doi: 10.1016/j.ejphar.2010.04.026. Epub 2010 May 4. Eur J Pharmacol. 2010. PMID: 20447386

8

Tamoxifen inhibits cardiac ATP-sensitive and acetylcholine-activated K+ currents in part by interfering with phosphatidylinositol 4,5-bisphosphate-channel interaction.

Ponce-Balbuena D, Moreno-Galindo EG, López-Izquierdo A, Ferrer T, Sánchez-Chapula JA. Ponce-Balbuena D, et al. J Pharmacol Sci. 2010;113(1):66-75. doi: 10.1254/jphs.10024fp. J Pharmacol Sci. 2010. PMID: 20472984 Free article.

9

Carvedilol inhibits Kir2.3 channels by interference with PIP₂-channel interaction.

Ferrer T, Ponce-Balbuena D, López-Izquierdo A, Aréchiga-Figueroa IA, de Boer TP, van der Heyden MA, Sánchez-Chapula JA. Ferrer T, et al. Eur J Pharmacol. 2011 Oct 1;668(1-2):72-7. doi: 10.1016/j.ejphar.2011.05.067. Epub 2011 Jun 6. Eur J Pharmacol. 2011. PMID: 21663737

10

Mechanisms for Kir channel inhibition by quinacrine: acute pore block of Kir2.x channels and interference in PIP2 interaction with Kir2.x and Kir6.2 channels.

López-Izquierdo A, Aréchiga-Figueroa IA, Moreno-Galindo EG, Ponce-Balbuena D, Rodríguez-Martínez M, Ferrer-Villada T, Rodríguez-Menchaca AA, van der Heyden MA, Sánchez-Chapula JA. López-Izquierdo A, et al. Pflugers Arch. 2011 Oct;462(4):505-17. doi: 10.1007/s00424-011-0995-5. Epub 2011 Jul 22. Pflugers Arch. 2011. PMID: 21779761

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