Du CY - Search Results

1

Enhanced inhibitory effect of acidosis on hERG potassium channels that incorporate the hERG1b isoform.

Du CY, El Harchi A, McPate MJ, Orchard CH, Hancox JC. Du CY, et al. Biochem Biophys Res Commun. 2011 Feb 11;405(2):222-7. doi: 10.1016/j.bbrc.2011.01.014. Epub 2011 Jan 8. Biochem Biophys Res Commun. 2011. PMID: 21219869

2

Acidosis impairs the protective role of hERG K(+) channels against premature stimulation.

Du CY, Adeniran I, Cheng H, Zhang YH, El Harchi A, McPate MJ, Zhang H, Orchard CH, Hancox JC. Du CY, et al. J Cardiovasc Electrophysiol. 2010 Oct;21(10):1160-9. doi: 10.1111/j.1540-8167.2010.01772.x. J Cardiovasc Electrophysiol. 2010. PMID: 20455975

3

Pharmacological inhibition of the hERG potassium channel is modulated by extracellular but not intracellular acidosis.

DU CY, El Harchi A, Zhang YH, Orchard CH, Hancox JC. DU CY, et al. J Cardiovasc Electrophysiol. 2011 Oct;22(10):1163-70. doi: 10.1111/j.1540-8167.2011.02060.x. Epub 2011 Apr 13. J Cardiovasc Electrophysiol. 2011. PMID: 21489024

4

High potency inhibition of hERG potassium channels by the sodium-calcium exchange inhibitor KB-R7943.

Cheng H, Zhang Y, Du C, Dempsey CE, Hancox JC. Cheng H, et al. Br J Pharmacol. 2012 Apr;165(7):2260-73. doi: 10.1111/j.1476-5381.2011.01688.x. Br J Pharmacol. 2012. PMID: 21950687 Free PMC article.

5

Topical antiangiogenic SRPK1 inhibitors reduce choroidal neovascularization in rodent models of exudative AMD.

Gammons MV, Fedorov O, Ivison D, Du C, Clark T, Hopkins C, Hagiwara M, Dick AD, Cox R, Harper SJ, Hancox JC, Knapp S, Bates DO. Gammons MV, et al. Invest Ophthalmol Vis Sci. 2013 Sep 5;54(9):6052-62. doi: 10.1167/iovs.13-12422. Invest Ophthalmol Vis Sci. 2013. PMID: 23887803 Free PMC article.

6

Modification by KCNE1 variants of the hERG potassium channel response to premature stimulation and to pharmacological inhibition.

Du C, El Harchi A, Zhang H, Hancox JC. Du C, et al. Physiol Rep. 2013 Nov;1(6):e00175. doi: 10.1002/phy2.175. Epub 2013 Nov 29. Physiol Rep. 2013. PMID: 24400172 Free PMC article.

7

Ranolazine inhibition of hERG potassium channels: drug-pore interactions and reduced potency against inactivation mutants.

Du C, Zhang Y, El Harchi A, Dempsey CE, Hancox JC. Du C, et al. J Mol Cell Cardiol. 2014 Sep;74(100):220-30. doi: 10.1016/j.yjmcc.2014.05.013. Epub 2014 May 27. J Mol Cell Cardiol. 2014. PMID: 24877995 Free PMC article.

8

Modification of KCNH2-encoded cardiac potassium channels by KCNE1 polymorphism.

Hancox JC, Du C, El Harchi A, Zhang H. Hancox JC, et al. Circ J. 2014;78(9):2330. doi: 10.1253/circj.cj-14-0513. Epub 2014 Jul 10. Circ J. 2014. PMID: 25008780 No abstract available.

9

A novel genetic modifier for clarithromycin-related cardiac arrhythmia risk?

Hancox JC, Du C, Harchi AE, Baranchuk A, Zhang H. Hancox JC, et al. Ther Adv Infect Dis. 2014 Apr;2(2):71-2. doi: 10.1177/2049936114522996. Ther Adv Infect Dis. 2014. PMID: 25165557 Free PMC article. No abstract available.

10

Suppression of the hERG potassium channel response to premature stimulation by reduction in extracellular potassium concentration.

Melgari D, Du C, El Harchi A, Zhang Y, Hancox JC. Melgari D, et al. Physiol Rep. 2014 Oct 15;2(10):e12165. doi: 10.14814/phy2.12165. Print 2014 Oct 1. Physiol Rep. 2014. PMID: 25318749 Free PMC article.

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