Goldsmith M - Search Results

1

Directed evolution of hydrolases for prevention of G-type nerve agent intoxication.

Gupta RD, Goldsmith M, Ashani Y, Simo Y, Mullokandov G, Bar H, Ben-David M, Leader H, Margalit R, Silman I, Sussman JL, Tawfik DS. Gupta RD, et al. Among authors: goldsmith m. Nat Chem Biol. 2011 Feb;7(2):120-5. doi: 10.1038/nchembio.510. Epub 2011 Jan 9. Nat Chem Biol. 2011. PMID: 21217689

2

Avoiding and controlling double transformation artifacts.

Goldsmith M, Kiss C, Bradbury AR, Tawfik DS. Goldsmith M, et al. Protein Eng Des Sel. 2007 Jul;20(7):315-8. doi: 10.1093/protein/gzm026. Epub 2007 Jun 15. Protein Eng Des Sel. 2007. PMID: 17575283

3

Potential role of phenotypic mutations in the evolution of protein expression and stability.

Goldsmith M, Tawfik DS. Goldsmith M, et al. Proc Natl Acad Sci U S A. 2009 Apr 14;106(15):6197-202. doi: 10.1073/pnas.0809506106. Epub 2009 Apr 1. Proc Natl Acad Sci U S A. 2009. PMID: 19339491 Free PMC article.

4

Stereo-specific synthesis of analogs of nerve agents and their utilization for selection and characterization of paraoxonase (PON1) catalytic scavengers.

Ashani Y, Gupta RD, Goldsmith M, Silman I, Sussman JL, Tawfik DS, Leader H. Ashani Y, et al. Among authors: goldsmith m. Chem Biol Interact. 2010 Sep 6;187(1-3):362-9. doi: 10.1016/j.cbi.2010.02.039. Epub 2010 Mar 19. Chem Biol Interact. 2010. PMID: 20303930 Free PMC article.

5

In vitro detoxification of cyclosarin in human blood pre-incubated ex vivo with recombinant serum paraoxonases.

Ashani Y, Goldsmith M, Leader H, Silman I, Sussman JL, Tawfik DS. Ashani Y, et al. Among authors: goldsmith m. Toxicol Lett. 2011 Sep 25;206(1):24-8. doi: 10.1016/j.toxlet.2011.07.017. Epub 2011 Jul 23. Toxicol Lett. 2011. PMID: 21807078 Free PMC article.

6

Computational redesign of a mononuclear zinc metalloenzyme for organophosphate hydrolysis.

Khare SD, Kipnis Y, Greisen P Jr, Takeuchi R, Ashani Y, Goldsmith M, Song Y, Gallaher JL, Silman I, Leader H, Sussman JL, Stoddard BL, Tawfik DS, Baker D. Khare SD, et al. Among authors: goldsmith m. Nat Chem Biol. 2012 Feb 5;8(3):294-300. doi: 10.1038/nchembio.777. Nat Chem Biol. 2012. PMID: 22306579 Free PMC article.

7

Evolved stereoselective hydrolases for broad-spectrum G-type nerve agent detoxification.

Goldsmith M, Ashani Y, Simo Y, Ben-David M, Leader H, Silman I, Sussman JL, Tawfik DS. Goldsmith M, et al. Chem Biol. 2012 Apr 20;19(4):456-66. doi: 10.1016/j.chembiol.2012.01.017. Chem Biol. 2012. PMID: 22520752

8

Directed enzyme evolution: beyond the low-hanging fruit.

Goldsmith M, Tawfik DS. Goldsmith M, et al. Curr Opin Struct Biol. 2012 Aug;22(4):406-12. doi: 10.1016/j.sbi.2012.03.010. Epub 2012 May 12. Curr Opin Struct Biol. 2012. PMID: 22579412 Review.

9

Enzyme engineering by targeted libraries.

Goldsmith M, Tawfik DS. Goldsmith M, et al. Methods Enzymol. 2013;523:257-83. doi: 10.1016/B978-0-12-394292-0.00012-6. Methods Enzymol. 2013. PMID: 23422434

10

Efficacy of the rePON1 mutant IIG1 to prevent cyclosarin toxicity in vivo and to detoxify structurally different nerve agents in vitro.

Worek F, Seeger T, Goldsmith M, Ashani Y, Leader H, Sussman JS, Tawfik D, Thiermann H, Wille T. Worek F, et al. Among authors: goldsmith m. Arch Toxicol. 2014 Jun;88(6):1257-66. doi: 10.1007/s00204-014-1204-z. Epub 2014 Jan 30. Arch Toxicol. 2014. PMID: 24477626

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

817 results

Search Page

Filters