Koob GF - Search Results

1

Cocaine analog coupled to disrupted adenovirus: a vaccine strategy to evoke high-titer immunity against addictive drugs.

Hicks MJ, De BP, Rosenberg JB, Davidson JT, Moreno AY, Janda KD, Wee S, Koob GF, Hackett NR, Kaminsky SM, Worgall S, Toth M, Mezey JG, Crystal RG. Hicks MJ, et al. Among authors: koob gf. Mol Ther. 2011 Mar;19(3):612-9. doi: 10.1038/mt.2010.280. Epub 2011 Jan 4. Mol Ther. 2011. PMID: 21206484 Free PMC article.

2

Anti-cocaine vaccine based on coupling a cocaine analog to a disrupted adenovirus.

Koob G, Hicks MJ, Wee S, Rosenberg JB, De BP, Kaminsky SM, Moreno A, Janda KD, Crystal RG. Koob G, et al. CNS Neurol Disord Drug Targets. 2011 Dec;10(8):899-904. doi: 10.2174/187152711799219334. CNS Neurol Disord Drug Targets. 2011. PMID: 22229312 Free PMC article. Review.

3

AAVrh.10-mediated expression of an anti-cocaine antibody mediates persistent passive immunization that suppresses cocaine-induced behavior.

Rosenberg JB, Hicks MJ, De BP, Pagovich O, Frenk E, Janda KD, Wee S, Koob GF, Hackett NR, Kaminsky SM, Worgall S, Tignor N, Mezey JG, Crystal RG. Rosenberg JB, et al. Among authors: koob gf. Hum Gene Ther. 2012 May;23(5):451-9. doi: 10.1089/hum.2011.178. Hum Gene Ther. 2012. PMID: 22486244 Free PMC article.

4

Disrupted adenovirus-based vaccines against small addictive molecules circumvent anti-adenovirus immunity.

De BP, Pagovich OE, Hicks MJ, Rosenberg JB, Moreno AY, Janda KD, Koob GF, Worgall S, Kaminsky SM, Sondhi D, Crystal RG. De BP, et al. Among authors: koob gf. Hum Gene Ther. 2013 Jan;24(1):58-66. doi: 10.1089/hum.2012.163. Epub 2012 Dec 21. Hum Gene Ther. 2013. PMID: 23140508 Free PMC article.

5

Adenovirus capsid-based anti-cocaine vaccine prevents cocaine from binding to the nonhuman primate CNS dopamine transporter.

Maoz A, Hicks MJ, Vallabhjosula S, Synan M, Kothari PJ, Dyke JP, Ballon DJ, Kaminsky SM, De BP, Rosenberg JB, Martinez D, Koob GF, Janda KD, Crystal RG. Maoz A, et al. Among authors: koob gf. Neuropsychopharmacology. 2013 Oct;38(11):2170-8. doi: 10.1038/npp.2013.114. Epub 2013 May 10. Neuropsychopharmacology. 2013. PMID: 23660705 Free PMC article.

6

Fate of systemically administered cocaine in nonhuman primates treated with the dAd5GNE anticocaine vaccine.

Hicks MJ, Kaminsky SM, De BP, Rosenberg JB, Evans SM, Foltin RW, Andrenyak DM, Moody DE, Koob GF, Janda KD, Ricart Arbona RJ, Lepherd ML, Crystal RG. Hicks MJ, et al. Among authors: koob gf. Hum Gene Ther Clin Dev. 2014 Mar;25(1):40-9. doi: 10.1089/humc.2013.231. Hum Gene Ther Clin Dev. 2014. PMID: 24649839 Free PMC article.

7

Novel cocaine vaccine linked to a disrupted adenovirus gene transfer vector blocks cocaine psychostimulant and reinforcing effects.

Wee S, Hicks MJ, De BP, Rosenberg JB, Moreno AY, Kaminsky SM, Janda KD, Crystal RG, Koob GF. Wee S, et al. Among authors: koob gf. Neuropsychopharmacology. 2012 Apr;37(5):1083-91. doi: 10.1038/npp.2011.200. Epub 2011 Sep 14. Neuropsychopharmacology. 2012. PMID: 21918504 Free PMC article.

8

Probing the effects of hapten stability on cocaine vaccine immunogenicity.

Cai X, Whitfield T, Moreno AY, Grant Y, Hixon MS, Koob GF, Janda KD. Cai X, et al. Among authors: koob gf. Mol Pharm. 2013 Nov 4;10(11):4176-84. doi: 10.1021/mp400214w. Epub 2013 Oct 4. Mol Pharm. 2013. PMID: 23927436 Free PMC article.

9

A critical evaluation of a nicotine vaccine within a self-administration behavioral model.

Moreno AY, Azar MR, Warren NA, Dickerson TJ, Koob GF, Janda KD. Moreno AY, et al. Among authors: koob gf. Mol Pharm. 2010 Apr 5;7(2):431-41. doi: 10.1021/mp900213u. Mol Pharm. 2010. PMID: 20104903

10

The role of the dynorphin-kappa opioid system in the reinforcing effects of drugs of abuse.

Wee S, Koob GF. Wee S, et al. Among authors: koob gf. Psychopharmacology (Berl). 2010 Jun;210(2):121-35. doi: 10.1007/s00213-010-1825-8. Epub 2010 Mar 30. Psychopharmacology (Berl). 2010. PMID: 20352414 Free PMC article. Review.

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