Vargas HM - Search Results

1

BeKm-1, a peptide inhibitor of human ether-a-go-go-related gene potassium currents, prolongs QTc intervals in isolated rabbit heart.

Qu Y, Fang M, Gao B, Chui RW, Vargas HM. Qu Y, et al. Among authors: vargas hm. J Pharmacol Exp Ther. 2011 Apr;337(1):2-8. doi: 10.1124/jpet.110.176883. Epub 2010 Dec 23. J Pharmacol Exp Ther. 2011. PMID: 21205913

2

Assessment of two external telemetry systems (PhysioJacket and JET) in beagle dogs with telemetry implants.

Chui RW, Fosdick A, Conner R, Jiang J, Bruenner BA, Vargas HM. Chui RW, et al. Among authors: vargas hm. J Pharmacol Toxicol Methods. 2009 Jul-Aug;60(1):58-68. doi: 10.1016/j.vascn.2009.04.196. Epub 2009 May 5. J Pharmacol Toxicol Methods. 2009. PMID: 19426820

3

A comparison of three software platforms for automated ECG analysis.

Chui RW, Vargas HM. Chui RW, et al. Among authors: vargas hm. J Pharmacol Toxicol Methods. 2009 Jul-Aug;60(1):28-38. doi: 10.1016/j.vascn.2009.05.004. Epub 2009 May 23. J Pharmacol Toxicol Methods. 2009. PMID: 19467337

4

A new preclinical biomarker for risk of Torsades de Pointes: drug-induced reduction of the cardiac electromechanical window.

Vargas HM. Vargas HM. Br J Pharmacol. 2010 Dec;161(7):1441-3. doi: 10.1111/j.1476-5381.2010.00980.x. Br J Pharmacol. 2010. PMID: 20698854 Free PMC article.

5

hERG potency estimates based upon dose solution analysis: What have we learned?

Qu Y, Schnier P, Zanon R, Vargas HM. Qu Y, et al. Among authors: vargas hm. J Pharmacol Toxicol Methods. 2011 Nov-Dec;64(3):251-7. doi: 10.1016/j.vascn.2011.08.004. Epub 2011 Aug 23. J Pharmacol Toxicol Methods. 2011. PMID: 21888984

6

Comprehensive analysis of cardiac arrhythmias in telemetered cynomolgus monkeys over a 6 month period.

Chui RW, Derakhchan K, Vargas HM. Chui RW, et al. Among authors: vargas hm. J Pharmacol Toxicol Methods. 2012 Sep;66(2):84-91. doi: 10.1016/j.vascn.2012.05.002. Epub 2012 May 14. J Pharmacol Toxicol Methods. 2012. PMID: 22613062

7

Itraconazole decreases left ventricular contractility in isolated rabbit heart: mechanism of action.

Qu Y, Fang M, Gao B, Amouzadeh HR, Li N, Narayanan P, Acton P, Lawrence J, Vargas HM. Qu Y, et al. Among authors: vargas hm. Toxicol Appl Pharmacol. 2013 Apr 15;268(2):113-22. doi: 10.1016/j.taap.2013.01.029. Epub 2013 Feb 13. Toxicol Appl Pharmacol. 2013. PMID: 23416206

8

Human embryonic stem cell derived cardiac myocytes detect hERG-mediated repolarization effects, but not Nav1.5 induced depolarization delay.

Qu Y, Gao B, Fang M, Vargas HM. Qu Y, et al. Among authors: vargas hm. J Pharmacol Toxicol Methods. 2013 Jul-Aug;68(1):74-81. doi: 10.1016/j.vascn.2013.03.001. Epub 2013 Mar 19. J Pharmacol Toxicol Methods. 2013. PMID: 23518063

9

Detection of QTc interval prolongation using jacket telemetry in conscious non-human primates: comparison with implanted telemetry.

Derakhchan K, Chui RW, Stevens D, Gu W, Vargas HM. Derakhchan K, et al. Among authors: vargas hm. Br J Pharmacol. 2014 Jan;171(2):509-22. doi: 10.1111/bph.12484. Br J Pharmacol. 2014. PMID: 24372552 Free PMC article.

10

Oxytocin does not directly alter cardiac repolarization in rabbit or human cardiac myocytes.

Qu Y, Fang M, Gao B, Amagasu S, Crumb WJ, Vargas HM. Qu Y, et al. Among authors: vargas hm. Pharmacol Res Perspect. 2015 Feb;3(1):e00102. doi: 10.1002/prp2.102. Epub 2014 Dec 9. Pharmacol Res Perspect. 2015. PMID: 25692020 Free PMC article.

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