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Apoptosis signal-regulating kinase 1 and cyclin D1 compose a positive feedback loop contributing to tumor growth in gastric cancer.
Hayakawa Y, Hirata Y, Nakagawa H, Sakamoto K, Hikiba Y, Kinoshita H, Nakata W, Takahashi R, Tateishi K, Tada M, Akanuma M, Yoshida H, Takeda K, Ichijo H, Omata M, Maeda S, Koike K. Hayakawa Y, et al. Among authors: hikiba y. Proc Natl Acad Sci U S A. 2011 Jan 11;108(2):780-5. doi: 10.1073/pnas.1011418108. Epub 2010 Dec 27. Proc Natl Acad Sci U S A. 2011. PMID: 21187402 Free PMC article.
Apoptosis signal-regulating kinase 1 regulates colitis and colitis-associated tumorigenesis by the innate immune responses.
Hayakawa Y, Hirata Y, Nakagawa H, Sakamoto K, Hikiba Y, Otsuka M, Ijichi H, Ikenoue T, Tateishi K, Akanuma M, Ogura K, Yoshida H, Ichijo H, Omata M, Maeda S. Hayakawa Y, et al. Among authors: hikiba y. Gastroenterology. 2010 Mar;138(3):1055-67.e1-4. doi: 10.1053/j.gastro.2009.11.015. Epub 2009 Nov 18. Gastroenterology. 2010. PMID: 19931259
Therapeutic effect of c-Jun N-terminal kinase inhibition on pancreatic cancer.
Takahashi R, Hirata Y, Sakitani K, Nakata W, Kinoshita H, Hayakawa Y, Nakagawa H, Sakamoto K, Hikiba Y, Ijichi H, Moses HL, Maeda S, Koike K. Takahashi R, et al. Among authors: hikiba y. Cancer Sci. 2013 Mar;104(3):337-44. doi: 10.1111/cas.12080. Epub 2013 Jan 24. Cancer Sci. 2013. PMID: 23237571 Free PMC article.
Interleukin-6 mediates epithelial-stromal interactions and promotes gastric tumorigenesis.
Kinoshita H, Hirata Y, Nakagawa H, Sakamoto K, Hayakawa Y, Takahashi R, Nakata W, Sakitani K, Serizawa T, Hikiba Y, Akanuma M, Shibata W, Maeda S, Koike K. Kinoshita H, et al. Among authors: hikiba y. PLoS One. 2013 Apr 12;8(4):e60914. doi: 10.1371/journal.pone.0060914. Print 2013. PLoS One. 2013. PMID: 23593346 Free PMC article.
Loss of liver E-cadherin induces sclerosing cholangitis and promotes carcinogenesis.
Nakagawa H, Hikiba Y, Hirata Y, Font-Burgada J, Sakamoto K, Hayakawa Y, Taniguchi K, Umemura A, Kinoshita H, Sakitani K, Nishikawa Y, Hirano K, Ikenoue T, Ijichi H, Dhar D, Shibata W, Akanuma M, Koike K, Karin M, Maeda S. Nakagawa H, et al. Among authors: hikiba y. Proc Natl Acad Sci U S A. 2014 Jan 21;111(3):1090-5. doi: 10.1073/pnas.1322731111. Epub 2014 Jan 6. Proc Natl Acad Sci U S A. 2014. PMID: 24395807 Free PMC article.
Different effects of point mutations within the B-Raf glycine-rich loop in colorectal tumors on mitogen-activated protein/extracellular signal-regulated kinase kinase/extracellular signal-regulated kinase and nuclear factor kappaB pathway and cellular transformation.
Ikenoue T, Hikiba Y, Kanai F, Aragaki J, Tanaka Y, Imamura J, Imamura T, Ohta M, Ijichi H, Tateishi K, Kawakami T, Matsumura M, Kawabe T, Omata M. Ikenoue T, et al. Among authors: hikiba y. Cancer Res. 2004 May 15;64(10):3428-35. doi: 10.1158/0008-5472.CAN-03-3591. Cancer Res. 2004. PMID: 15150094
59 results