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Chimpanzee/human mAbs to vaccinia virus B5 protein neutralize vaccinia and smallpox viruses and protect mice against vaccinia virus.
Chen Z, Earl P, Americo J, Damon I, Smith SK, Zhou YH, Yu F, Sebrell A, Emerson S, Cohen G, Eisenberg RJ, Svitel J, Schuck P, Satterfield W, Moss B, Purcell R. Chen Z, et al. Proc Natl Acad Sci U S A. 2006 Feb 7;103(6):1882-7. doi: 10.1073/pnas.0510598103. Epub 2006 Jan 25. Proc Natl Acad Sci U S A. 2006. PMID: 16436502 Free PMC article.
Characterization of chimpanzee/human monoclonal antibodies to vaccinia virus A33 glycoprotein and its variola virus homolog in vitro and in a vaccinia virus mouse protection model.
Chen Z, Earl P, Americo J, Damon I, Smith SK, Yu F, Sebrell A, Emerson S, Cohen G, Eisenberg RJ, Gorshkova I, Schuck P, Satterfield W, Moss B, Purcell R. Chen Z, et al. J Virol. 2007 Sep;81(17):8989-95. doi: 10.1128/JVI.00906-07. Epub 2007 Jun 20. J Virol. 2007. PMID: 17581986 Free PMC article.
B cell gene signature with massive intrahepatic production of antibodies to hepatitis B core antigen in hepatitis B virus-associated acute liver failure.
Farci P, Diaz G, Chen Z, Govindarajan S, Tice A, Agulto L, Pittaluga S, Boon D, Yu C, Engle RE, Haas M, Simon R, Purcell RH, Zamboni F. Farci P, et al. Among authors: chen z. Proc Natl Acad Sci U S A. 2010 May 11;107(19):8766-71. doi: 10.1073/pnas.1003854107. Epub 2010 Apr 26. Proc Natl Acad Sci U S A. 2010. PMID: 20421498 Free PMC article.
Delayed treatment with W1-mAb, a chimpanzee-derived monoclonal antibody against protective antigen, reduces mortality from challenges with anthrax edema or lethal toxin in rats and with anthrax spores in mice.
Altaweel L, Chen Z, Moayeri M, Cui X, Li Y, Su J, Fitz Y, Johnson S, Leppla SH, Purcell R, Eichacker PQ. Altaweel L, et al. Among authors: chen z. Crit Care Med. 2011 Jun;39(6):1439-47. doi: 10.1097/CCM.0b013e3182120691. Crit Care Med. 2011. PMID: 21336113 Free PMC article.
76,329 results
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