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High IGF-IR activity in triple-negative breast cancer cell lines and tumorgrafts correlates with sensitivity to anti-IGF-IR therapy.
Litzenburger BC, Creighton CJ, Tsimelzon A, Chan BT, Hilsenbeck SG, Wang T, Carboni JM, Gottardis MM, Huang F, Chang JC, Lewis MT, Rimawi MF, Lee AV. Litzenburger BC, et al. Among authors: lewis mt. Clin Cancer Res. 2011 Apr 15;17(8):2314-27. doi: 10.1158/1078-0432.CCR-10-1903. Epub 2010 Dec 22. Clin Cancer Res. 2011. PMID: 21177763 Free PMC article.
Constitutively active type I insulin-like growth factor receptor causes transformation and xenograft growth of immortalized mammary epithelial cells and is accompanied by an epithelial-to-mesenchymal transition mediated by NF-kappaB and snail.
Kim HJ, Litzenburger BC, Cui X, Delgado DA, Grabiner BC, Lin X, Lewis MT, Gottardis MM, Wong TW, Attar RM, Carboni JM, Lee AV. Kim HJ, et al. Among authors: lewis mt. Mol Cell Biol. 2007 Apr;27(8):3165-75. doi: 10.1128/MCB.01315-06. Epub 2007 Feb 12. Mol Cell Biol. 2007. PMID: 17296734 Free PMC article.
Intrinsic resistance of tumorigenic breast cancer cells to chemotherapy.
Li X, Lewis MT, Huang J, Gutierrez C, Osborne CK, Wu MF, Hilsenbeck SG, Pavlick A, Zhang X, Chamness GC, Wong H, Rosen J, Chang JC. Li X, et al. Among authors: lewis mt. J Natl Cancer Inst. 2008 May 7;100(9):672-9. doi: 10.1093/jnci/djn123. Epub 2008 Apr 29. J Natl Cancer Inst. 2008. PMID: 18445819
Decreased TGFbeta signaling and increased COX2 expression in high risk women with increased mammographic breast density.
Yang WT, Lewis MT, Hess K, Wong H, Tsimelzon A, Karadag N, Cairo M, Wei C, Meric-Bernstam F, Brown P, Arun B, Hortobagyi GN, Sahin A, Chang JC. Yang WT, et al. Among authors: lewis mt. Breast Cancer Res Treat. 2010 Jan;119(2):305-14. doi: 10.1007/s10549-009-0350-0. Epub 2009 Feb 25. Breast Cancer Res Treat. 2010. PMID: 19241157 Free PMC article.
Androgen receptor overexpression induces tamoxifen resistance in human breast cancer cells.
De Amicis F, Thirugnansampanthan J, Cui Y, Selever J, Beyer A, Parra I, Weigel NL, Herynk MH, Tsimelzon A, Lewis MT, Chamness GC, Hilsenbeck SG, Andò S, Fuqua SA. De Amicis F, et al. Among authors: lewis mt. Breast Cancer Res Treat. 2010 May;121(1):1-11. doi: 10.1007/s10549-009-0436-8. Epub 2009 Jun 17. Breast Cancer Res Treat. 2010. PMID: 19533338 Free PMC article.
188 results