Shokat KM - Search Results

1

Phosphoproteomic analysis reveals interconnected system-wide responses to perturbations of kinases and phosphatases in yeast.

Bodenmiller B, Wanka S, Kraft C, Urban J, Campbell D, Pedrioli PG, Gerrits B, Picotti P, Lam H, Vitek O, Brusniak MY, Roschitzki B, Zhang C, Shokat KM, Schlapbach R, Colman-Lerner A, Nolan GP, Nesvizhskii AI, Peter M, Loewith R, von Mering C, Aebersold R. Bodenmiller B, et al. Among authors: shokat km. Sci Signal. 2010 Dec 21;3(153):rs4. doi: 10.1126/scisignal.2001182. Sci Signal. 2010. PMID: 21177495 Free PMC article.

2

The Saccharomyces cerevisiae Mob2p-Cbk1p kinase complex promotes polarized growth and acts with the mitotic exit network to facilitate daughter cell-specific localization of Ace2p transcription factor.

Weiss EL, Kurischko C, Zhang C, Shokat K, Drubin DG, Luca FC. Weiss EL, et al. J Cell Biol. 2002 Sep 2;158(5):885-900. doi: 10.1083/jcb.200203094. Epub 2002 Aug 26. J Cell Biol. 2002. PMID: 12196508 Free PMC article.

3

Chemical genetic analysis of Apg1 reveals a non-kinase role in the induction of autophagy.

Abeliovich H, Zhang C, Dunn WA Jr, Shokat KM, Klionsky DJ. Abeliovich H, et al. Among authors: shokat km. Mol Biol Cell. 2003 Feb;14(2):477-90. doi: 10.1091/mbc.e02-07-0413. Mol Biol Cell. 2003. PMID: 12589048 Free PMC article.

4

Bypassing a kinase activity with an ATP-competitive drug.

Papa FR, Zhang C, Shokat K, Walter P. Papa FR, et al. Science. 2003 Nov 28;302(5650):1533-7. doi: 10.1126/science.1090031. Epub 2003 Oct 16. Science. 2003. PMID: 14564015

5

Mek1 kinase activity functions downstream of RED1 in the regulation of meiotic double strand break repair in budding yeast.

Wan L, de los Santos T, Zhang C, Shokat K, Hollingsworth NM. Wan L, et al. Mol Biol Cell. 2004 Jan;15(1):11-23. doi: 10.1091/mbc.e03-07-0499. Epub 2003 Oct 31. Mol Biol Cell. 2004. PMID: 14595109 Free PMC article.

6

Chemical genetics reveals a role for Mps1 kinase in kinetochore attachment during mitosis.

Jones MH, Huneycutt BJ, Pearson CG, Zhang C, Morgan G, Shokat K, Bloom K, Winey M. Jones MH, et al. Curr Biol. 2005 Jan 26;15(2):160-5. doi: 10.1016/j.cub.2005.01.010. Curr Biol. 2005. PMID: 15668173 Free article.

7

Structural bioinformatics-based design of selective, irreversible kinase inhibitors.

Cohen MS, Zhang C, Shokat KM, Taunton J. Cohen MS, et al. Among authors: shokat km. Science. 2005 May 27;308(5726):1318-21. doi: 10.1126/science1108367. Science. 2005. PMID: 15919995 Free PMC article.

8

Chemical inactivation of cdc7 kinase in budding yeast results in a reversible arrest that allows efficient cell synchronization prior to meiotic recombination.

Wan L, Zhang C, Shokat KM, Hollingsworth NM. Wan L, et al. Among authors: shokat km. Genetics. 2006 Dec;174(4):1767-74. doi: 10.1534/genetics.106.064303. Epub 2006 Oct 22. Genetics. 2006. PMID: 17057233 Free PMC article.

9

Access denied: Snf1 activation loop phosphorylation is controlled by availability of the phosphorylated threonine 210 to the PP1 phosphatase.

Rubenstein EM, McCartney RR, Zhang C, Shokat KM, Shirra MK, Arndt KM, Schmidt MC. Rubenstein EM, et al. Among authors: shokat km. J Biol Chem. 2008 Jan 4;283(1):222-230. doi: 10.1074/jbc.M707957200. Epub 2007 Nov 8. J Biol Chem. 2008. PMID: 17991748 Free PMC article.

10

A coupled chemical-genetic and bioinformatic approach to Polo-like kinase pathway exploration.

Snead JL, Sullivan M, Lowery DM, Cohen MS, Zhang C, Randle DH, Taunton J, Yaffe MB, Morgan DO, Shokat KM. Snead JL, et al. Among authors: shokat km. Chem Biol. 2007 Nov;14(11):1261-72. doi: 10.1016/j.chembiol.2007.09.011. Chem Biol. 2007. PMID: 18022565 Free PMC article.

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