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Dopamine D1-histamine H3 receptor heteromers provide a selective link to MAPK signaling in GABAergic neurons of the direct striatal pathway.
Moreno E, Hoffmann H, Gonzalez-Sepúlveda M, Navarro G, Casadó V, Cortés A, Mallol J, Vignes M, McCormick PJ, Canela EI, Lluís C, Moratalla R, Ferré S, Ortiz J, Franco R. Moreno E, et al. Among authors: moratalla r. J Biol Chem. 2011 Feb 18;286(7):5846-54. doi: 10.1074/jbc.M110.161489. Epub 2010 Dec 20. J Biol Chem. 2011. PMID: 21173143 Free PMC article.
Striatal adenosine A2A and cannabinoid CB1 receptors form functional heteromeric complexes that mediate the motor effects of cannabinoids.
Carriba P, Ortiz O, Patkar K, Justinova Z, Stroik J, Themann A, Müller C, Woods AS, Hope BT, Ciruela F, Casadó V, Canela EI, Lluis C, Goldberg SR, Moratalla R, Franco R, Ferré S. Carriba P, et al. Among authors: moratalla r. Neuropsychopharmacology. 2007 Nov;32(11):2249-59. doi: 10.1038/sj.npp.1301375. Epub 2007 Mar 14. Neuropsychopharmacology. 2007. PMID: 17356572
Prolonged treatment with pramipexole promotes physical interaction of striatal dopamine D3 autoreceptors with dopamine transporters to reduce dopamine uptake.
Castro-Hernández J, Afonso-Oramas D, Cruz-Muros I, Salas-Hernández J, Barroso-Chinea P, Moratalla R, Millan MJ, González-Hernández T. Castro-Hernández J, et al. Among authors: moratalla r. Neurobiol Dis. 2015 Feb;74:325-35. doi: 10.1016/j.nbd.2014.12.007. Epub 2014 Dec 12. Neurobiol Dis. 2015. PMID: 25511804
145 results