Zhang Q - Search Results

1

Novel pyrrolopyrimidine-based α-helix mimetics: cell-permeable inhibitors of protein−protein interactions.

Lee JH, Zhang Q, Jo S, Chai SC, Oh M, Im W, Lu H, Lim HS. Lee JH, et al. Among authors: zhang q. J Am Chem Soc. 2011 Feb 2;133(4):676-9. doi: 10.1021/ja108230s. J Am Chem Soc. 2011. PMID: 21171592 Free PMC article.

2

Identification of small molecules affecting p53-MDM2/MDMX interaction by fluorescence polarization.

Zhang Q, Lu H. Zhang Q, et al. Methods Mol Biol. 2013;962:95-111. doi: 10.1007/978-1-62703-236-0_8. Methods Mol Biol. 2013. PMID: 23150440 Free PMC article.

3

Nutlin's two roads toward apoptosis.

Zhang Q, Lu H. Zhang Q, et al. Cancer Biol Ther. 2010 Sep 15;10(6):579-81. doi: 10.4161/cbt.10.6.13127. Epub 2010 Sep 24. Cancer Biol Ther. 2010. PMID: 20716967 Free PMC article. No abstract available.

4

Hydrophilic residues are crucial for ribosomal protein L11 (RPL11) interaction with zinc finger domain of MDM2 and p53 protein activation.

Zhang Q, Xiao H, Chai SC, Hoang QQ, Lu H. Zhang Q, et al. J Biol Chem. 2011 Nov 4;286(44):38264-38274. doi: 10.1074/jbc.M111.277012. Epub 2011 Sep 8. J Biol Chem. 2011. PMID: 21903592 Free PMC article.

5

A small molecule Inauhzin inhibits SIRT1 activity and suppresses tumour growth through activation of p53.

Zhang Q, Zeng SX, Zhang Y, Zhang Y, Ding D, Ye Q, Meroueh SO, Lu H. Zhang Q, et al. Among authors: zhang y. EMBO Mol Med. 2012 Apr;4(4):298-312. doi: 10.1002/emmm.201100211. Epub 2012 Feb 13. EMBO Mol Med. 2012. PMID: 22331558 Free PMC article.

6

Structure and activity analysis of Inauhzin analogs as novel antitumor compounds that induce p53 and inhibit cell growth.

Zhang Q, Ding D, Zeng SX, Ye QZ, Lu H. Zhang Q, et al. PLoS One. 2012;7(10):e46294. doi: 10.1371/journal.pone.0046294. Epub 2012 Oct 24. PLoS One. 2012. PMID: 23115626 Free PMC article.

7

Targeting p53-MDM2-MDMX loop for cancer therapy.

Zhang Q, Zeng SX, Lu H. Zhang Q, et al. Subcell Biochem. 2014;85:281-319. doi: 10.1007/978-94-017-9211-0_16. Subcell Biochem. 2014. PMID: 25201201 Free PMC article. Review.

8

Inauhzin and Nutlin3 synergistically activate p53 and suppress tumor growth.

Zhang Y, Zhang Q, Zeng SX, Zhang Y, Mayo LD, Lu H. Zhang Y, et al. Among authors: zhang q. Cancer Biol Ther. 2012 Aug;13(10):915-24. doi: 10.4161/cbt.20844. Epub 2012 Aug 1. Cancer Biol Ther. 2012. PMID: 22785205 Free PMC article.

9

Inauhzin sensitizes p53-dependent cytotoxicity and tumor suppression of chemotherapeutic agents.

Zhang Y, Zhang Q, Zeng SX, Hao Q, Lu H. Zhang Y, et al. Among authors: zhang q. Neoplasia. 2013 May;15(5):523-34. doi: 10.1593/neo.13142. Neoplasia. 2013. PMID: 23633924 Free PMC article.

10

The role of IMP dehydrogenase 2 in Inauhzin-induced ribosomal stress.

Zhang Q, Zhou X, Wu R, Mosley A, Zeng SX, Xing Z, Lu H. Zhang Q, et al. Elife. 2014 Oct 27;3:e03077. doi: 10.7554/eLife.03077. Elife. 2014. PMID: 25347121 Free PMC article.

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