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A novel biased allosteric compound inhibitor of parturition selectively impedes the prostaglandin F2alpha-mediated Rho/ROCK signaling pathway.
Goupil E, Tassy D, Bourguet C, Quiniou C, Wisehart V, Pétrin D, Le Gouill C, Devost D, Zingg HH, Bouvier M, Saragovi HU, Chemtob S, Lubell WD, Claing A, Hébert TE, Laporte SA. Goupil E, et al. Among authors: le gouill c. J Biol Chem. 2010 Aug 13;285(33):25624-36. doi: 10.1074/jbc.M110.115196. Epub 2010 Jun 15. J Biol Chem. 2010. PMID: 20551320 Free PMC article.
Mapping physiological G protein-coupled receptor signaling pathways reveals a role for receptor phosphorylation in airway contraction.
Bradley SJ, Wiegman CH, Iglesias MM, Kong KC, Butcher AJ, Plouffe B, Goupil E, Bourgognon JM, Macedo-Hatch T, LeGouill C, Russell K, Laporte SA, König GM, Kostenis E, Bouvier M, Chung KF, Amrani Y, Tobin AB. Bradley SJ, et al. Proc Natl Acad Sci U S A. 2016 Apr 19;113(16):4524-9. doi: 10.1073/pnas.1521706113. Epub 2016 Apr 8. Proc Natl Acad Sci U S A. 2016. PMID: 27071102 Free PMC article.
Mapping GPR88-Venus illuminates a novel role for GPR88 in sensory processing.
Ehrlich AT, Semache M, Bailly J, Wojcik S, Arefin TM, Colley C, Le Gouill C, Gross F, Lukasheva V, Hogue M, Darcq E, Harsan LA, Bouvier M, Kieffer BL. Ehrlich AT, et al. Among authors: le gouill c. Brain Struct Funct. 2018 Apr;223(3):1275-1296. doi: 10.1007/s00429-017-1547-3. Epub 2017 Nov 6. Brain Struct Funct. 2018. PMID: 29110094 Free PMC article.
58 results