Peersen OB - Search Results

1

Structural basis for active site closure by the poliovirus RNA-dependent RNA polymerase.

Gong P, Peersen OB. Gong P, et al. Among authors: peersen ob. Proc Natl Acad Sci U S A. 2010 Dec 28;107(52):22505-10. doi: 10.1073/pnas.1007626107. Epub 2010 Dec 10. Proc Natl Acad Sci U S A. 2010. PMID: 21148772 Free PMC article.

2

Structural basis for proteolysis-dependent activation of the poliovirus RNA-dependent RNA polymerase.

Thompson AA, Peersen OB. Thompson AA, et al. Among authors: peersen ob. EMBO J. 2004 Sep 1;23(17):3462-71. doi: 10.1038/sj.emboj.7600357. Epub 2004 Aug 12. EMBO J. 2004. PMID: 15306852 Free PMC article.

3

Stabilization of poliovirus polymerase by NTP binding and fingers-thumb interactions.

Thompson AA, Albertini RA, Peersen OB. Thompson AA, et al. Among authors: peersen ob. J Mol Biol. 2007 Mar 9;366(5):1459-74. doi: 10.1016/j.jmb.2006.11.070. Epub 2006 Dec 1. J Mol Biol. 2007. PMID: 17223130 Free PMC article.

4

Crystal structure of coxsackievirus B3 3Dpol highlights the functional importance of residue 5 in picornavirus polymerases.

Campagnola G, Weygandt M, Scoggin K, Peersen O. Campagnola G, et al. J Virol. 2008 Oct;82(19):9458-64. doi: 10.1128/JVI.00647-08. Epub 2008 Jul 16. J Virol. 2008. PMID: 18632862 Free PMC article.

5

A quantitative stopped-flow fluorescence assay for measuring polymerase elongation rates.

Gong P, Campagnola G, Peersen OB. Gong P, et al. Among authors: peersen ob. Anal Biochem. 2009 Aug 1;391(1):45-55. doi: 10.1016/j.ab.2009.04.035. Epub 2009 May 3. Anal Biochem. 2009. PMID: 19406094 Free PMC article.

6

Poliovirus polymerase residue 5 plays a critical role in elongation complex stability.

Hobdey SE, Kempf BJ, Steil BP, Barton DJ, Peersen OB. Hobdey SE, et al. Among authors: peersen ob. J Virol. 2010 Aug;84(16):8072-84. doi: 10.1128/JVI.02147-09. Epub 2010 Jun 9. J Virol. 2010. PMID: 20534858 Free PMC article.

7

High-throughput screening identification of poliovirus RNA-dependent RNA polymerase inhibitors.

Campagnola G, Gong P, Peersen OB. Campagnola G, et al. Among authors: peersen ob. Antiviral Res. 2011 Sep;91(3):241-51. doi: 10.1016/j.antiviral.2011.06.006. Epub 2011 Jun 21. Antiviral Res. 2011. PMID: 21722674 Free PMC article.

8

A template RNA entry channel in the fingers domain of the poliovirus polymerase.

Kortus MG, Kempf BJ, Haworth KG, Barton DJ, Peersen OB. Kortus MG, et al. Among authors: peersen ob. J Mol Biol. 2012 Apr 6;417(4):263-78. doi: 10.1016/j.jmb.2012.01.049. Epub 2012 Feb 1. J Mol Biol. 2012. PMID: 22321798 Free PMC article.

9

Coxsackievirus B3 mutator strains are attenuated in vivo.

Gnädig NF, Beaucourt S, Campagnola G, Bordería AV, Sanz-Ramos M, Gong P, Blanc H, Peersen OB, Vignuzzi M. Gnädig NF, et al. Among authors: peersen ob. Proc Natl Acad Sci U S A. 2012 Aug 21;109(34):E2294-303. doi: 10.1073/pnas.1204022109. Epub 2012 Aug 1. Proc Natl Acad Sci U S A. 2012. PMID: 22853955 Free PMC article.

10

Structural features of a picornavirus polymerase involved in the polyadenylation of viral RNA.

Kempf BJ, Kelly MM, Springer CL, Peersen OB, Barton DJ. Kempf BJ, et al. Among authors: peersen ob. J Virol. 2013 May;87(10):5629-44. doi: 10.1128/JVI.02590-12. Epub 2013 Mar 6. J Virol. 2013. PMID: 23468507 Free PMC article.

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