Connelly S - Search Results

1

A structural analysis of M protein in coronavirus assembly and morphology.

Neuman BW, Kiss G, Kunding AH, Bhella D, Baksh MF, Connelly S, Droese B, Klaus JP, Makino S, Sawicki SG, Siddell SG, Stamou DG, Wilson IA, Kuhn P, Buchmeier MJ. Neuman BW, et al. Among authors: connelly s. J Struct Biol. 2011 Apr;174(1):11-22. doi: 10.1016/j.jsb.2010.11.021. Epub 2010 Dec 3. J Struct Biol. 2011. PMID: 21130884 Free PMC article.

2

Structure-based design of kinetic stabilizers that ameliorate the transthyretin amyloidoses.

Connelly S, Choi S, Johnson SM, Kelly JW, Wilson IA. Connelly S, et al. Curr Opin Struct Biol. 2010 Feb;20(1):54-62. doi: 10.1016/j.sbi.2009.12.009. Epub 2010 Feb 3. Curr Opin Struct Biol. 2010. PMID: 20133122 Free PMC article. Review.

3

Chemoselective small molecules that covalently modify one lysine in a non-enzyme protein in plasma.

Choi S, Connelly S, Reixach N, Wilson IA, Kelly JW. Choi S, et al. Among authors: connelly s. Nat Chem Biol. 2010 Feb;6(2):133-9. doi: 10.1038/nchembio.281. Nat Chem Biol. 2010. PMID: 20081815 Free PMC article.

4

Toward optimization of the second aryl substructure common to transthyretin amyloidogenesis inhibitors using biochemical and structural studies.

Johnson SM, Connelly S, Wilson IA, Kelly JW. Johnson SM, et al. Among authors: connelly s. J Med Chem. 2009 Feb 26;52(4):1115-25. doi: 10.1021/jm801347s. J Med Chem. 2009. PMID: 19191553 Free PMC article.

5

Toward optimization of the linker substructure common to transthyretin amyloidogenesis inhibitors using biochemical and structural studies.

Johnson SM, Connelly S, Wilson IA, Kelly JW. Johnson SM, et al. Among authors: connelly s. J Med Chem. 2008 Oct 23;51(20):6348-58. doi: 10.1021/jm800435s. Epub 2008 Sep 24. J Med Chem. 2008. PMID: 18811132 Free PMC article.

6

Biochemical and structural evaluation of highly selective 2-arylbenzoxazole-based transthyretin amyloidogenesis inhibitors.

Johnson SM, Connelly S, Wilson IA, Kelly JW. Johnson SM, et al. Among authors: connelly s. J Med Chem. 2008 Jan 24;51(2):260-70. doi: 10.1021/jm0708735. Epub 2007 Dec 21. J Med Chem. 2008. PMID: 18095641

7

Biological and structural evaluation of 10R- and 10S-methylthio-DDACTHF reveals a new role for sulfur in inhibition of glycinamide ribonucleotide transformylase.

Connelly S, DeMartino JK, Boger DL, Wilson IA. Connelly S, et al. Biochemistry. 2013 Jul 30;52(30):5133-44. doi: 10.1021/bi4005182. Epub 2013 Jul 19. Biochemistry. 2013. PMID: 23869564 Free PMC article.

8

A simple solid phase, peptide-based fluorescent assay for the efficient and universal screening of HRV 3C protease inhibitors.

Schünemann K, Connelly S, Kowalczyk R, Sperry J, Wilson IA, Fraser JD, Brimble MA. Schünemann K, et al. Among authors: connelly s. Bioorg Med Chem Lett. 2012 Aug 1;22(15):5018-24. doi: 10.1016/j.bmcl.2012.06.015. Epub 2012 Jun 15. Bioorg Med Chem Lett. 2012. PMID: 22763202

9

Asymmetric synthesis of inhibitors of glycinamide ribonucleotide transformylase.

DeMartino JK, Hwang I, Connelly S, Wilson IA, Boger DL. DeMartino JK, et al. Among authors: connelly s. J Med Chem. 2008 Sep 11;51(17):5441-8. doi: 10.1021/jm800555h. Epub 2008 Aug 8. J Med Chem. 2008. PMID: 18686942 Free PMC article.

10

A substructure combination strategy to create potent and selective transthyretin kinetic stabilizers that prevent amyloidogenesis and cytotoxicity.

Choi S, Reixach N, Connelly S, Johnson SM, Wilson IA, Kelly JW. Choi S, et al. Among authors: connelly s. J Am Chem Soc. 2010 Feb 3;132(4):1359-70. doi: 10.1021/ja908562q. J Am Chem Soc. 2010. PMID: 20043671 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

392 results

Search Page

Filters