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The glycoprotein precursor gene of Junin virus determines the virulence of the Romero strain and the attenuation of the Candid #1 strain in a representative animal model of Argentine hemorrhagic fever.
Seregin AV, Yun NE, Miller M, Aronson J, Smith JK, Walker AG, Smith JN, Huang C, Manning JT, de la Torre JC, Paessler S. Seregin AV, et al. J Virol. 2015 Jun;89(11):5949-56. doi: 10.1128/JVI.00104-15. Epub 2015 Mar 25. J Virol. 2015. PMID: 25810546 Free PMC article.
Absence of an N-Linked Glycosylation Motif in the Glycoprotein of the Live-Attenuated Argentine Hemorrhagic Fever Vaccine, Candid #1, Results in Its Improper Processing, and Reduced Surface Expression.
Manning JT, Seregin AV, Yun NE, Koma T, Huang C, Barral J, de la Torre JC, Paessler S. Manning JT, et al. Among authors: seregin av. Front Cell Infect Microbiol. 2017 Feb 6;7:20. doi: 10.3389/fcimb.2017.00020. eCollection 2017. Front Cell Infect Microbiol. 2017. PMID: 28220142 Free PMC article.
A single mutation (V64G) within the RING Domain of Z attenuates Junin virus.
Hallam SJ, Manning JT, Maruyama J, Seregin A, Huang C, Walker DH, de la Torre JC, Paessler S. Hallam SJ, et al. PLoS Negl Trop Dis. 2020 Sep 25;14(9):e0008555. doi: 10.1371/journal.pntd.0008555. eCollection 2020 Sep. PLoS Negl Trop Dis. 2020. PMID: 32976538 Free PMC article.
Functional interferon system is required for clearance of lassa virus.
Yun NE, Poussard AL, Seregin AV, Walker AG, Smith JK, Aronson JF, Smith JN, Soong L, Paessler S. Yun NE, et al. Among authors: seregin av. J Virol. 2012 Mar;86(6):3389-92. doi: 10.1128/JVI.06284-11. Epub 2012 Jan 11. J Virol. 2012. PMID: 22238311 Free PMC article.
45 results