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Stable IgG-like bispecific antibodies directed toward the type I insulin-like growth factor receptor demonstrate enhanced ligand blockade and anti-tumor activity.
Dong J, Sereno A, Snyder WB, Miller BR, Tamraz S, Doern A, Favis M, Wu X, Tran H, Langley E, Joseph I, Boccia A, Kelly R, Wortham K, Wang Q, Berquist L, Huang F, Gao SX, Zhang Y, Lugovskoy A, Martin S, Gouvis H, Berkowitz S, Chiang G, Reff M, Glaser SM, Hariharan K, Demarest SJ. Dong J, et al. Among authors: tran h. J Biol Chem. 2011 Feb 11;286(6):4703-17. doi: 10.1074/jbc.M110.184317. Epub 2010 Dec 1. J Biol Chem. 2011. PMID: 21123183 Free PMC article.
Characterization of inhibitory anti-insulin-like growth factor receptor antibodies with different epitope specificity and ligand-blocking properties: implications for mechanism of action in vivo.
Doern A, Cao X, Sereno A, Reyes CL, Altshuler A, Huang F, Hession C, Flavier A, Favis M, Tran H, Ailor E, Levesque M, Murphy T, Berquist L, Tamraz S, Snipas T, Garber E, Shestowsky WS, Rennard R, Graff CP, Wu X, Snyder W, Cole L, Gregson D, Shields M, Ho SN, Reff ME, Glaser SM, Dong J, Demarest SJ, Hariharan K. Doern A, et al. Among authors: tran h. J Biol Chem. 2009 Apr 10;284(15):10254-67. doi: 10.1074/jbc.M809709200. Epub 2009 Feb 11. J Biol Chem. 2009. PMID: 19211557 Free PMC article.
The Impact of Tumor Stage and Histopathology on Survival Outcomes in Esophageal Cancer Patients over the Past Decade.
Bangolo A, Nagesh VK, Simonson G, Thapa A, Ram A, Santhakumari NJ, Chamroukh R, Varughese VJ, Nareeba S, Menon A, Sridharan K, Chacko AA, Mansour C, Elias D, Singh GR, Rambaransingh A, Mendez LR, Levy C, Kianifar Aguilar I, Hamad I, Sharma U, Salcedo J, Tran HH, Haq A, Geleto TB, Jean K, Periel L, Bravin S, Weissman S. Bangolo A, et al. Among authors: tran hh. Med Sci (Basel). 2024 Dec 9;12(4):70. doi: 10.3390/medsci12040070. Med Sci (Basel). 2024. PMID: 39728419 Free PMC article.
High peripheral T cell diversity is associated with lower risk of toxicity and superior response to dual immune checkpoint inhibitor therapy in patients with metastatic NSCLC.
Altan M, Li R, Li Z, Chen R, Sheshadri A, Tran HT, Little L, Baguley J, Sinson J, Vokes N, Gandhi S, Antonoff MB, Swisher SG, Lizee G, Reuben A, Heymach JV, Zhang J. Altan M, et al. Among authors: tran ht. J Immunother Cancer. 2024 Dec 25;12(12):e008950. doi: 10.1136/jitc-2024-008950. J Immunother Cancer. 2024. PMID: 39721752 Free PMC article. Clinical Trial.
3,181 results