Bleickardt CJ - Search Results

1

Characterization of the selective mGluR1 antagonist, JNJ16259685, in rodent models of movement and coordination.

Hodgson RA, Hyde LA, Guthrie DH, Cohen-Williams ME, Leach PT, Kazdoba TM, Bleickardt CJ, Lu SX, Parker EM, Varty GB. Hodgson RA, et al. Among authors: bleickardt cj. Pharmacol Biochem Behav. 2011 Apr;98(2):181-7. doi: 10.1016/j.pbb.2010.11.018. Epub 2010 Nov 28. Pharmacol Biochem Behav. 2011. PMID: 21122808

2

Antagonism of the adenosine A2A receptor attenuates akathisia-like behavior induced with MP-10 or aripiprazole in a novel non-human primate model.

Bleickardt CJ, Kazdoba TM, Jones NT, Hunter JC, Hodgson RA. Bleickardt CJ, et al. Pharmacol Biochem Behav. 2014 Mar;118:36-45. doi: 10.1016/j.pbb.2013.10.030. Epub 2013 Nov 8. Pharmacol Biochem Behav. 2014. PMID: 24211858

3

Characterization of a novel vasopressin V1b receptor antagonist, V1B-30N, in animal models of anxiety-like and depression-like behavior.

Hodgson RA, Mullins D, Lu SX, Guzzi M, Zhang X, Bleickardt CJ, Scott JD, Miller MW, Stamford AW, Parker EM, Varty GB. Hodgson RA, et al. Among authors: bleickardt cj. Eur J Pharmacol. 2014 May 5;730:157-63. doi: 10.1016/j.ejphar.2014.02.027. Epub 2014 Mar 4. Eur J Pharmacol. 2014. PMID: 24602808

4

Effects of the selective adenosine A2A receptor antagonist, SCH 412348, on the parkinsonian phenotype of MitoPark mice.

Smith KM, Browne SE, Jayaraman S, Bleickardt CJ, Hodge LM, Lis E, Yao L, Rittle SL, Innocent N, Mullins DE, Boykow G, Reynolds IJ, Hill D, Parker EM, Hodgson RA. Smith KM, et al. Among authors: bleickardt cj. Eur J Pharmacol. 2014 Apr 5;728:31-8. doi: 10.1016/j.ejphar.2014.01.052. Epub 2014 Jan 31. Eur J Pharmacol. 2014. PMID: 24486705

5

Characterization of the V1a antagonist, JNJ-17308616, in rodent models of anxiety-like behavior.

Bleickardt CJ, Mullins DE, Macsweeney CP, Werner BJ, Pond AJ, Guzzi MF, Martin FD, Varty GB, Hodgson RA. Bleickardt CJ, et al. Psychopharmacology (Berl). 2009 Mar;202(4):711-8. doi: 10.1007/s00213-008-1354-x. Epub 2008 Oct 16. Psychopharmacology (Berl). 2009. PMID: 18923820

6

Adenosine A(2A) Receptor Antagonists Do Not Disrupt Rodent Prepulse Inhibition: An Improved Side Effect Profile in the Treatment of Parkinson's Disease.

Bleickardt CJ, Lashomb AL, Merkel CE, Hodgson RA. Bleickardt CJ, et al. Parkinsons Dis. 2012;2012:591094. doi: 10.1155/2012/591094. Epub 2011 Dec 4. Parkinsons Dis. 2012. PMID: 22191072 Free PMC article.

7

A2A receptor antagonists do not induce dyskinesias in drug-naive or L-dopa sensitized rats.

Jones N, Bleickardt C, Mullins D, Parker E, Hodgson R. Jones N, et al. Brain Res Bull. 2013 Sep;98:163-9. doi: 10.1016/j.brainresbull.2013.07.001. Epub 2013 Jul 6. Brain Res Bull. 2013. PMID: 23838432

8

Discovery of orally active pyrazoloquinolines as potent PDE10 inhibitors for the management of schizophrenia.

Yang SW, Smotryski J, McElroy WT, Tan Z, Ho G, Tulshian D, Greenlee WJ, Guzzi M, Zhang X, Mullins D, Xiao L, Hruza A, Chan TM, Rindgen D, Bleickardt C, Hodgson R. Yang SW, et al. Bioorg Med Chem Lett. 2012 Jan 1;22(1):235-9. doi: 10.1016/j.bmcl.2011.11.023. Epub 2011 Nov 16. Bioorg Med Chem Lett. 2012. PMID: 22142545

9

Pyrazoloquinolines as PDE10A inhibitors: discovery of a tool compound.

McElroy WT, Tan Z, Basu K, Yang SW, Smotryski J, Ho GD, Tulshian D, Greenlee WJ, Mullins D, Guzzi M, Zhang X, Bleickardt C, Hodgson R. McElroy WT, et al. Bioorg Med Chem Lett. 2012 Feb 1;22(3):1335-9. doi: 10.1016/j.bmcl.2011.12.080. Epub 2011 Dec 21. Bioorg Med Chem Lett. 2012. PMID: 22227212

10

The discovery of potent, selective, and orally active pyrazoloquinolines as PDE10A inhibitors for the treatment of Schizophrenia.

Ho GD, Yang SW, Smotryski J, Bercovici A, Nechuta T, Smith EM, McElroy W, Tan Z, Tulshian D, McKittrick B, Greenlee WJ, Hruza A, Xiao L, Rindgen D, Mullins D, Guzzi M, Zhang X, Bleickardt C, Hodgson R. Ho GD, et al. Bioorg Med Chem Lett. 2012 Jan 15;22(2):1019-22. doi: 10.1016/j.bmcl.2011.11.127. Epub 2011 Dec 9. Bioorg Med Chem Lett. 2012. PMID: 22222034

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