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Map2k4 functions as a tumor suppressor in lung adenocarcinoma and inhibits tumor cell invasion by decreasing peroxisome proliferator-activated receptor γ2 expression.
Ahn YH, Yang Y, Gibbons DL, Creighton CJ, Yang F, Wistuba II, Lin W, Thilaganathan N, Alvarez CA, Roybal J, Goldsmith EJ, Tournier C, Kurie JM. Ahn YH, et al. Among authors: yang f, yang y. Mol Cell Biol. 2011 Nov;31(21):4270-85. doi: 10.1128/MCB.05562-11. Epub 2011 Sep 6. Mol Cell Biol. 2011. PMID: 21896780 Free PMC article.
Fibulin-2 is a driver of malignant progression in lung adenocarcinoma.
Baird BN, Schliekelman MJ, Ahn YH, Chen Y, Roybal JD, Gill BJ, Mishra DK, Erez B, O'Reilly M, Yang Y, Patel M, Liu X, Thilaganathan N, Larina IV, Dickinson ME, West JL, Gibbons DL, Liu DD, Kim MP, Hicks JM, Wistuba II, Hanash SM, Kurie JM. Baird BN, et al. Among authors: yang y. PLoS One. 2013 Jun 10;8(6):e67054. doi: 10.1371/journal.pone.0067054. Print 2013. PLoS One. 2013. PMID: 23785517 Free PMC article.
ZEB1 sensitizes lung adenocarcinoma to metastasis suppression by PI3K antagonism.
Yang Y, Ahn YH, Chen Y, Tan X, Guo L, Gibbons DL, Ungewiss C, Peng DH, Liu X, Lin SH, Thilaganathan N, Wistuba II, Rodriguez-Canales J, McLendon G, Creighton CJ, Kurie JM. Yang Y, et al. J Clin Invest. 2014 Jun;124(6):2696-708. doi: 10.1172/JCI72171. Epub 2014 Apr 24. J Clin Invest. 2014. PMID: 24762440 Free PMC article.
A genetic cell context-dependent role for ZEB1 in lung cancer.
Zhang T, Guo L, Creighton CJ, Lu Q, Gibbons DL, Yi ES, Deng B, Molina JR, Sun Z, Yang P, Yang Y. Zhang T, et al. Among authors: yang p, yang y. Nat Commun. 2016 Jul 26;7:12231. doi: 10.1038/ncomms12231. Nat Commun. 2016. PMID: 27456471 Free PMC article.
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