Pingoud A - Search Results

1

Structural insights into catalytic and substrate binding mechanisms of the strategic EndA nuclease from Streptococcus pneumoniae.

Moon AF, Midon M, Meiss G, Pingoud A, London RE, Pedersen LC. Moon AF, et al. Among authors: pingoud a. Nucleic Acids Res. 2011 Apr;39(7):2943-53. doi: 10.1093/nar/gkq1152. Epub 2010 Nov 26. Nucleic Acids Res. 2011. PMID: 21113026 Free PMC article.

2

The nuclease a-inhibitor complex is characterized by a novel metal ion bridge.

Ghosh M, Meiss G, Pingoud AM, London RE, Pedersen LC. Ghosh M, et al. J Biol Chem. 2007 Feb 23;282(8):5682-90. doi: 10.1074/jbc.M605986200. Epub 2006 Nov 30. J Biol Chem. 2007. PMID: 17138564 Free PMC article.

3

Structural insights into the mechanism of nuclease A, a betabeta alpha metal nuclease from Anabaena.

Ghosh M, Meiss G, Pingoud A, London RE, Pedersen LC. Ghosh M, et al. Among authors: pingoud a. J Biol Chem. 2005 Jul 29;280(30):27990-7. doi: 10.1074/jbc.M501798200. Epub 2005 May 15. J Biol Chem. 2005. PMID: 15897201 Free article.

4

Mutational and biochemical analysis of the DNA-entry nuclease EndA from Streptococcus pneumoniae.

Midon M, Schäfer P, Pingoud A, Ghosh M, Moon AF, Cuneo MJ, London RE, Meiss G. Midon M, et al. Among authors: pingoud a. Nucleic Acids Res. 2011 Jan;39(2):623-34. doi: 10.1093/nar/gkq802. Epub 2010 Sep 15. Nucleic Acids Res. 2011. PMID: 20846957 Free PMC article.

5

Inhibitors of Streptococcus pneumoniae surface endonuclease EndA discovered by high-throughput screening using a PicoGreen fluorescence assay.

Peterson EJ, Kireev D, Moon AF, Midon M, Janzen WP, Pingoud A, Pedersen LC, Singleton SF. Peterson EJ, et al. Among authors: pingoud a. J Biomol Screen. 2013 Mar;18(3):247-57. doi: 10.1177/1087057112461153. Epub 2012 Sep 26. J Biomol Screen. 2013. PMID: 23015019 Free PMC article.

6

Chemical rescue of active site mutants of S. pneumoniae surface endonuclease EndA and other nucleases of the HNH family by imidazole.

Midon M, Gimadutdinow O, Meiss G, Friedhoff P, Pingoud A. Midon M, et al. Among authors: pingoud a. Chembiochem. 2012 Mar 19;13(5):713-21. doi: 10.1002/cbic.201100775. Epub 2012 Feb 17. Chembiochem. 2012. PMID: 22344704 Free article.

7

Involvement of conserved histidine, lysine and tyrosine residues in the mechanism of DNA cleavage by the caspase-3 activated DNase CAD.

Korn C, Scholz SR, Gimadutdinow O, Pingoud A, Meiss G. Korn C, et al. Among authors: pingoud a. Nucleic Acids Res. 2002 Mar 15;30(6):1325-32. doi: 10.1093/nar/30.6.1325. Nucleic Acids Res. 2002. PMID: 11884629 Free PMC article.

8

The nuclease A inhibitor represents a new variation of the rare PR-1 fold.

Kirby TW, Mueller GA, DeRose EF, Lebetkin MS, Meiss G, Pingoud A, London RE. Kirby TW, et al. Among authors: pingoud a. J Mol Biol. 2002 Jul 19;320(4):771-82. doi: 10.1016/s0022-2836(02)00460-6. J Mol Biol. 2002. PMID: 12095254

9

Identification of functionally relevant histidine residues in the apoptotic nuclease CAD.

Meiss G, Scholz SR, Korn C, Gimadutdinow O, Pingoud A. Meiss G, et al. Among authors: pingoud a. Nucleic Acids Res. 2001 Oct 1;29(19):3901-9. doi: 10.1093/nar/29.19.3901. Nucleic Acids Res. 2001. PMID: 11574671 Free PMC article.

10

Structural and functional characterization of mitochondrial EndoG, a sugar non-specific nuclease which plays an important role during apoptosis.

Schäfer P, Scholz SR, Gimadutdinow O, Cymerman IA, Bujnicki JM, Ruiz-Carrillo A, Pingoud A, Meiss G. Schäfer P, et al. Among authors: pingoud a. J Mol Biol. 2004 Apr 23;338(2):217-28. doi: 10.1016/j.jmb.2004.02.069. J Mol Biol. 2004. PMID: 15066427 Free article.

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