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A subcutaneous adipose tissue-liver signalling axis controls hepatic gluconeogenesis.
Reilly SM, Ahmadian M, Zamarron BF, Chang L, Uhm M, Poirier B, Peng X, Krause DM, Korytnaya E, Neidert A, Liddle C, Yu RT, Lumeng CN, Oral EA, Downes M, Evans RM, Saltiel AR. Reilly SM, et al. Nat Commun. 2015 Jan 12;6:6047. doi: 10.1038/ncomms7047. Nat Commun. 2015. PMID: 25581158 Free PMC article. Clinical Trial.
Inhibition of IKKɛ and TBK1 Improves Glucose Control in a Subset of Patients with Type 2 Diabetes.
Oral EA, Reilly SM, Gomez AV, Meral R, Butz L, Ajluni N, Chenevert TL, Korytnaya E, Neidert AH, Hench R, Rus D, Horowitz JF, Poirier B, Zhao P, Lehmann K, Jain M, Yu R, Liddle C, Ahmadian M, Downes M, Evans RM, Saltiel AR. Oral EA, et al. Among authors: reilly sm. Cell Metab. 2017 Jul 5;26(1):157-170.e7. doi: 10.1016/j.cmet.2017.06.006. Cell Metab. 2017. PMID: 28683283 Free PMC article. Clinical Trial.
ERRγ Preserves Brown Fat Innate Thermogenic Activity.
Ahmadian M, Liu S, Reilly SM, Hah N, Fan W, Yoshihara E, Jha P, De Magalhaes Filho CD, Jacinto S, Gomez AV, Dai Y, Yu RT, Liddle C, Atkins AR, Auwerx J, Saltiel AR, Downes M, Evans RM. Ahmadian M, et al. Among authors: reilly sm. Cell Rep. 2018 Mar 13;22(11):2849-2859. doi: 10.1016/j.celrep.2018.02.061. Cell Rep. 2018. PMID: 29539415 Free PMC article.
YIPF6 controls sorting of FGF21 into COPII vesicles and promotes obesity.
Wang L, Mazagova M, Pan C, Yang S, Brandl K, Liu J, Reilly SM, Wang Y, Miao Z, Loomba R, Lu N, Guo Q, Liu J, Yu RT, Downes M, Evans RM, Brenner DA, Saltiel AR, Beutler B, Schnabl B. Wang L, et al. Among authors: reilly sm. Proc Natl Acad Sci U S A. 2019 Jul 23;116(30):15184-15193. doi: 10.1073/pnas.1904360116. Epub 2019 Jul 9. Proc Natl Acad Sci U S A. 2019. PMID: 31289229 Free PMC article.
121 results