Sharp PS - Search Results

1

Chronic systemic therapy with low-dose morpholino oligomers ameliorates the pathology and normalizes locomotor behavior in mdx mice.

Malerba A, Sharp PS, Graham IR, Arechavala-Gomeza V, Foster K, Muntoni F, Wells DJ, Dickson G. Malerba A, et al. Among authors: sharp ps. Mol Ther. 2011 Feb;19(2):345-54. doi: 10.1038/mt.2010.261. Epub 2010 Nov 23. Mol Ther. 2011. PMID: 21102560 Free PMC article.

2

Codon and mRNA sequence optimization of microdystrophin transgenes improves expression and physiological outcome in dystrophic mdx mice following AAV2/8 gene transfer.

Foster H, Sharp PS, Athanasopoulos T, Trollet C, Graham IR, Foster K, Wells DJ, Dickson G. Foster H, et al. Among authors: sharp ps. Mol Ther. 2008 Nov;16(11):1825-32. doi: 10.1038/mt.2008.186. Epub 2008 Sep 2. Mol Ther. 2008. PMID: 18766174 Free article.

3

Physiological characterization of muscle strength with variable levels of dystrophin restoration in mdx mice following local antisense therapy.

Sharp PS, Bye-a-Jee H, Wells DJ. Sharp PS, et al. Mol Ther. 2011 Jan;19(1):165-71. doi: 10.1038/mt.2010.213. Epub 2010 Oct 5. Mol Ther. 2011. PMID: 20924363 Free PMC article.

4

Transgenic overexpression of LARGE induces α-dystroglycan hyperglycosylation in skeletal and cardiac muscle.

Brockington M, Torelli S, Sharp PS, Liu K, Cirak S, Brown SC, Wells DJ, Muntoni F. Brockington M, et al. Among authors: sharp ps. PLoS One. 2010 Dec 28;5(12):e14434. doi: 10.1371/journal.pone.0014434. PLoS One. 2010. PMID: 21203384 Free PMC article.

5

Metformin treatment has no beneficial effect in a dose-response survival study in the SOD1(G93A) mouse model of ALS and is harmful in female mice.

Kaneb HM, Sharp PS, Rahmani-Kondori N, Wells DJ. Kaneb HM, et al. Among authors: sharp ps. PLoS One. 2011;6(9):e24189. doi: 10.1371/journal.pone.0024189. Epub 2011 Sep 1. PLoS One. 2011. PMID: 21909419 Free PMC article.

6

Heat shock protein 27 rescues motor neurons following nerve injury and preserves muscle function.

Sharp P, Krishnan M, Pullar O, Navarrete R, Wells D, de Belleroche J. Sharp P, et al. Exp Neurol. 2006 Apr;198(2):511-8. doi: 10.1016/j.expneurol.2005.12.031. Epub 2006 Feb 23. Exp Neurol. 2006. PMID: 16497297

7

Protective effects of heat shock protein 27 in a model of ALS occur in the early stages of disease progression.

Sharp PS, Akbar MT, Bouri S, Senda A, Joshi K, Chen HJ, Latchman DS, Wells DJ, de Belleroche J. Sharp PS, et al. Neurobiol Dis. 2008 Apr;30(1):42-55. doi: 10.1016/j.nbd.2007.12.002. Epub 2007 Dec 23. Neurobiol Dis. 2008. PMID: 18255302

8

Hypertensive retinopathy in Afro-Caribbeans and Europeans. Prevalence and risk factor relationships.

Sharp PS, Chaturvedi N, Wormald R, McKeigue PM, Marmot MG, Young SM. Sharp PS, et al. Hypertension. 1995 Jun;25(6):1322-5. doi: 10.1161/01.hyp.25.6.1322. Hypertension. 1995. PMID: 7768581

9

Graphene Oxide Nanoscale Platform Enhances the Anti-Cancer Properties of Bortezomib in Glioblastoma Models.

Sharp PS, Stylianou M, Arellano LM, Neves JC, Gravagnuolo AM, Dodd A, Barr K, Lozano N, Kisby T, Kostarelos K. Sharp PS, et al. Adv Healthc Mater. 2023 Jan;12(3):e2201968. doi: 10.1002/adhm.202201968. Epub 2022 Nov 11. Adv Healthc Mater. 2023. PMID: 36300643 Free PMC article.

10

Advanced molecular imaging for the characterisation of complex medicines.

Yilmaz D, Sharp PS, Main MJ, Simpson PB. Yilmaz D, et al. Among authors: sharp ps. Drug Discov Today. 2022 Jun;27(6):1716-1723. doi: 10.1016/j.drudis.2022.03.001. Epub 2022 Mar 4. Drug Discov Today. 2022. PMID: 35257858 Review.

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