Vekich S - Search Results

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Prediction of oral pharmacokinetics of cMet kinase inhibitors in humans: physiologically based pharmacokinetic model versus traditional one-compartment model.

Yamazaki S, Skaptason J, Romero D, Vekich S, Jones HM, Tan W, Wilner KD, Koudriakova T. Yamazaki S, et al. Among authors: vekich s. Drug Metab Dispos. 2011 Mar;39(3):383-93. doi: 10.1124/dmd.110.035857. Epub 2010 Nov 23. Drug Metab Dispos. 2011. PMID: 21098644 Clinical Trial.

Pharmacokinetic-pharmacodynamic modeling of biomarker response and tumor growth inhibition to an orally available heat shock protein 90 inhibitor in a human tumor xenograft mouse model.

Yamazaki S, Nguyen L, Vekich S, Shen Z, Yin MJ, Mehta PP, Kung PP, Vicini P. Yamazaki S, et al. Among authors: vekich s. J Pharmacol Exp Ther. 2011 Sep;338(3):964-73. doi: 10.1124/jpet.111.181339. Epub 2011 Jun 16. J Pharmacol Exp Ther. 2011. PMID: 21680888

Discovery pharmacokinetic studies in mice using serial microsampling, dried blood spots and microbore LC-MS/MS.

Rahavendran SV, Vekich S, Skor H, Batugo M, Nguyen L, Shetty B, Shen Z. Rahavendran SV, et al. Among authors: vekich s. Bioanalysis. 2012 May;4(9):1077-95. doi: 10.4155/bio.12.85. Bioanalysis. 2012. PMID: 22612688

Evaluation of intraocular pharmacokinetics and toxicity of prinomastat (AG3340) in the rabbit.

Cheng L, Rivero ME, Garcia CR, McDermott CD, Keefe KS, Wiley CA, Soules KA, Bergeron-Lynn G, Vekich S, Zhang K, Appelt K, Freeman WR. Cheng L, et al. Among authors: vekich s. J Ocul Pharmacol Ther. 2001 Jun;17(3):295-304. doi: 10.1089/108076801750295326. J Ocul Pharmacol Ther. 2001. PMID: 11436949

Characterization of brimonidine metabolism with rat, rabbit, dog, monkey and human liver fractions and rabbit liver aldehyde oxidase.

Acheampong AA, Chien DS, Lam S, Vekich S, Breau A, Usansky J, Harcourt D, Munk SA, Nguyen H, Garst M, Tang-Liu D. Acheampong AA, et al. Among authors: vekich s. Xenobiotica. 1996 Oct;26(10):1035-55. doi: 10.3109/00498259609167421. Xenobiotica. 1996. PMID: 8905918

Quantitative contrast enhanced ultrasound and CT assessment of tumor response to antiangiogenic therapy in rats.

Pollard RE, Broumas AR, Wisner ER, Vekich SV, Ferrara KW. Pollard RE, et al. Among authors: vekich sv. Ultrasound Med Biol. 2007 Feb;33(2):235-45. doi: 10.1016/j.ultrasmedbio.2006.07.036. Ultrasound Med Biol. 2007. PMID: 17306694

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