Jones HM - Search Results

1

Prediction of oral pharmacokinetics of cMet kinase inhibitors in humans: physiologically based pharmacokinetic model versus traditional one-compartment model.

Yamazaki S, Skaptason J, Romero D, Vekich S, Jones HM, Tan W, Wilner KD, Koudriakova T. Yamazaki S, et al. Among authors: jones hm. Drug Metab Dispos. 2011 Mar;39(3):383-93. doi: 10.1124/dmd.110.035857. Epub 2010 Nov 23. Drug Metab Dispos. 2011. PMID: 21098644 Clinical Trial.

2

Preclinical and clinical pharmacokinetics of PF-02413873, a nonsteroidal progesterone receptor antagonist.

Bungay PJ, Tweedy S, Howe DC, Gibson KR, Jones HM, Mount NM. Bungay PJ, et al. Among authors: jones hm. Drug Metab Dispos. 2011 Aug;39(8):1396-405. doi: 10.1124/dmd.110.037234. Epub 2011 May 4. Drug Metab Dispos. 2011. PMID: 21543556 Clinical Trial.

3

Mechanistic pharmacokinetic modeling for the prediction of transporter-mediated disposition in humans from sandwich culture human hepatocyte data.

Jones HM, Barton HA, Lai Y, Bi YA, Kimoto E, Kempshall S, Tate SC, El-Kattan A, Houston JB, Galetin A, Fenner KS. Jones HM, et al. Drug Metab Dispos. 2012 May;40(5):1007-17. doi: 10.1124/dmd.111.042994. Epub 2012 Feb 16. Drug Metab Dispos. 2012. PMID: 22344703

4

Application of physiologically based pharmacokinetic modeling to understanding the clinical pharmacokinetics of UK-369,003.

Watson KJ, Davis J, Jones HM. Watson KJ, et al. Among authors: jones hm. Drug Metab Dispos. 2011 Jul;39(7):1203-13. doi: 10.1124/dmd.111.038224. Epub 2011 Mar 30. Drug Metab Dispos. 2011. PMID: 21451120

5

In vitro evaluation of hepatic transporter-mediated clinical drug-drug interactions: hepatocyte model optimization and retrospective investigation.

Bi YA, Kimoto E, Sevidal S, Jones HM, Barton HA, Kempshall S, Whalen KM, Zhang H, Ji C, Fenner KS, El-Kattan AF, Lai Y. Bi YA, et al. Among authors: jones hm. Drug Metab Dispos. 2012 Jun;40(6):1085-92. doi: 10.1124/dmd.111.043489. Epub 2012 Mar 1. Drug Metab Dispos. 2012. PMID: 22381335 Review.

6

Simulation of human intravenous and oral pharmacokinetics of 21 diverse compounds using physiologically based pharmacokinetic modelling.

Jones HM, Gardner IB, Collard WT, Stanley PJ, Oxley P, Hosea NA, Plowchalk D, Gernhardt S, Lin J, Dickins M, Rahavendran SR, Jones BC, Watson KJ, Pertinez H, Kumar V, Cole S. Jones HM, et al. Among authors: jones bc. Clin Pharmacokinet. 2011 May;50(5):331-47. doi: 10.2165/11539680-000000000-00000. Clin Pharmacokinet. 2011. PMID: 21456633

7

Pre-clinical pharmacokinetics of UK-453,061, a novel non-nucleoside reverse transcriptase inhibitor (NNRTI), and use of in silico physiologically based prediction tools to predict the oral pharmacokinetics of UK-453,061 in man.

Allan G, Davis J, Dickins M, Gardner I, Jenkins T, Jones H, Webster R, Westgate H. Allan G, et al. Xenobiotica. 2008 Jun;38(6):620-40. doi: 10.1080/00498250802069088. Xenobiotica. 2008. PMID: 18570162

8

Dose selection based on physiologically based pharmacokinetic (PBPK) approaches.

Jones HM, Mayawala K, Poulin P. Jones HM, et al. AAPS J. 2013 Apr;15(2):377-87. doi: 10.1208/s12248-012-9446-2. Epub 2012 Dec 27. AAPS J. 2013. PMID: 23269526 Free PMC article. Review.

9

A novel strategy for physiologically based predictions of human pharmacokinetics.

Jones HM, Parrott N, Jorga K, Lavé T. Jones HM, et al. Clin Pharmacokinet. 2006;45(5):511-42. doi: 10.2165/00003088-200645050-00006. Clin Pharmacokinet. 2006. PMID: 16640456

10

Prediction of human pharmacokinetics from preclinical information: comparative accuracy of quantitative prediction approaches.

Hosea NA, Collard WT, Cole S, Maurer TS, Fang RX, Jones H, Kakar SM, Nakai Y, Smith BJ, Webster R, Beaumont K. Hosea NA, et al. J Clin Pharmacol. 2009 May;49(5):513-33. doi: 10.1177/0091270009333209. Epub 2009 Mar 19. J Clin Pharmacol. 2009. PMID: 19299532

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

300 results

Search Page

Filters