Kungl AJ - Search Results

1

A new monocyte chemotactic protein-1/chemokine CC motif ligand-2 competitor limiting neointima formation and myocardial ischemia/reperfusion injury in mice.

Liehn EA, Piccinini AM, Koenen RR, Soehnlein O, Adage T, Fatu R, Curaj A, Popescu A, Zernecke A, Kungl AJ, Weber C. Liehn EA, et al. Among authors: kungl aj. J Am Coll Cardiol. 2010 Nov 23;56(22):1847-57. doi: 10.1016/j.jacc.2010.04.066. J Am Coll Cardiol. 2010. PMID: 21087715 Free article.

2

Disrupting functional interactions between platelet chemokines inhibits atherosclerosis in hyperlipidemic mice.

Koenen RR, von Hundelshausen P, Nesmelova IV, Zernecke A, Liehn EA, Sarabi A, Kramp BK, Piccinini AM, Paludan SR, Kowalska MA, Kungl AJ, Hackeng TM, Mayo KH, Weber C. Koenen RR, et al. Among authors: kungl aj. Nat Med. 2009 Jan;15(1):97-103. doi: 10.1038/nm.1898. Epub 2009 Jan 4. Nat Med. 2009. PMID: 19122657

3

Interfering with the CCL2-glycosaminoglycan axis as a potential approach to modulate neuroinflammation.

Gschwandtner M, Piccinini AM, Gerlza T, Adage T, Kungl AJ. Gschwandtner M, et al. Among authors: kungl aj. Neurosci Lett. 2016 Jul 28;626:164-73. doi: 10.1016/j.neulet.2016.05.037. Epub 2016 May 19. Neurosci Lett. 2016. PMID: 27212623

4

Targeting of CCL2-CCR2-Glycosaminoglycan Axis Using a CCL2 Decoy Protein Attenuates Metastasis through Inhibition of Tumor Cell Seeding.

Roblek M, Strutzmann E, Zankl C, Adage T, Heikenwalder M, Atlic A, Weis R, Kungl A, Borsig L. Roblek M, et al. Neoplasia. 2016 Jan;18(1):49-59. doi: 10.1016/j.neo.2015.11.013. Neoplasia. 2016. PMID: 26806351 Free PMC article.

5

Structure-based design of decoy chemokines as a way to explore the pharmacological potential of glycosaminoglycans.

Adage T, Piccinini AM, Falsone A, Trinker M, Robinson J, Gesslbauer B, Kungl AJ. Adage T, et al. Among authors: kungl aj. Br J Pharmacol. 2012 Nov;167(6):1195-205. doi: 10.1111/j.1476-5381.2012.02089.x. Br J Pharmacol. 2012. PMID: 22747966 Free PMC article. Review.

6

Designing a mutant CCL2-HSA chimera with high glycosaminoglycan-binding affinity and selectivity.

Gerlza T, Winkler S, Atlic A, Zankl C, Konya V, Kitic N, Strutzmann E, Knebl K, Adage T, Heinemann A, Weis R, Kungl AJ. Gerlza T, et al. Among authors: kungl aj. Protein Eng Des Sel. 2015 Aug;28(8):231-40. doi: 10.1093/protein/gzv025. Epub 2015 May 11. Protein Eng Des Sel. 2015. PMID: 25969511

7

Glycosaminoglycan silencing by engineered CXCL12 variants.

Gschwandtner M, Trinker MU, Hecher B, Adage T, Ali S, Kungl AJ. Gschwandtner M, et al. Among authors: kungl aj. FEBS Lett. 2015 Sep 14;589(19 Pt B):2819-24. doi: 10.1016/j.febslet.2015.07.052. Epub 2015 Aug 20. FEBS Lett. 2015. PMID: 26297821 Free article.

8

PA401, a novel CXCL8-based biologic therapeutic with increased glycosaminoglycan binding, reduces bronchoalveolar lavage neutrophils and systemic inflammatory markers in a murine model of LPS-induced lung inflammation.

Adage T, Del Bene F, Fiorentini F, Doornbos RP, Zankl C, Bartley MR, Kungl AJ. Adage T, et al. Among authors: kungl aj. Cytokine. 2015 Dec;76(2):433-441. doi: 10.1016/j.cyto.2015.08.006. Epub 2015 Aug 21. Cytokine. 2015. PMID: 26303011

9

Glycosaminoglycans are important mediators of neutrophilic inflammation in vivo.

Gschwandtner M, Strutzmann E, Teixeira MM, Anders HJ, Diedrichs-Möhring M, Gerlza T, Wildner G, Russo RC, Adage T, Kungl AJ. Gschwandtner M, et al. Among authors: kungl aj. Cytokine. 2017 Mar;91:65-73. doi: 10.1016/j.cyto.2016.12.008. Epub 2016 Dec 21. Cytokine. 2017. PMID: 28011398

10

The basic residue cluster (55)KKWVR(59) in CCL5 is required for in vivo biologic function.

Segerer S, Johnson Z, Rek A, Baltus T, von Hundelshausen P, Kungl AJ, Proudfoot AE, Weber C, Nelson PJ. Segerer S, et al. Among authors: kungl aj. Mol Immunol. 2009 Aug;46(13):2533-8. doi: 10.1016/j.molimm.2009.05.015. Epub 2009 Jun 12. Mol Immunol. 2009. PMID: 19524301

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